Voltammetric and LC-MS/MS Method for the determination of triclosan-a comparative study, validation and simultaneous application

Hana Dejmkova, Jiri Kwiecien, Karel Cizek, Jiri Cermak, Edita Vranova, Petra Mala, Jiri Zima, Jiri Barek

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In this paper, two determination methods of polychlorinated diphenylether triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol), an antibacterial and antifungal agent, are developed, compared and used in concordance. The first one, differential pulse voltammetry (DPV) on carbon paste electrode (CPE), is simple, fast, portable and inexpensive and therefore suitable for field measurements, large scale monitoring and screening purposes. The other one, liquid chromatography with MS/MS detection, is much more sophisticated, selective, accurate and sensitive (unfortunately much more expensive as well) and can serve for more reliable determination of triclosan in samples selected as suspicious during the screening measurements. Optimum conditions for both the determinations are described and validation parameters in matrices of drinking and river water are given.

Original languageEnglish
Pages (from-to)139-147
Number of pages9
JournalInternational Journal of Electrochemical Science
Volume9
Issue number1
Publication statusPublished - 1 Jan 2014
Externally publishedYes

Keywords

  • Carbon paste electrode
  • Differential pulse voltammetry
  • Multiple reaction monitoring
  • Pesticide
  • Triclosan

ASJC Scopus subject areas

  • Electrochemistry

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