Abstract
Abstract: Two methods, using glassy carbon paste electrode for the simultaneous determination homovanillic acid and vanillylmandelic acid, of two catecholamine neurotransmitter metabolites that can serve as biomarkers of several oncological diseases, were developed, based on differential pulse voltammetry and HPLC with amperometric detection. Low selectivity of the voltammetric method was limiting for the determination in urine samples; inclusion of chromatographic separation enabled the application in complex matrix. Graphical abstract: [Figure not available: see fulltext.]
| Original language | English |
|---|---|
| Pages (from-to) | 511-515 |
| Number of pages | 5 |
| Journal | Monatshefte fur Chemie |
| Volume | 148 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 Mar 2017 |
| Externally published | Yes |
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Keywords
- Electrochemistry
- High pressure liquid chromatography
- Homovanillic acid
- Vanillylmandelic acid
- Voltammetry
ASJC Scopus subject areas
- Chemistry(all)
Cite this
Voltammetric and amperometric determination of selected catecholamine metabolites using glassy carbon paste electrode. / Dejmkova, Hana; Adamkova, Hana; Barek, Jiri; Zima, Jiri.
In: Monatshefte fur Chemie, Vol. 148, No. 3, 01.03.2017, p. 511-515.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Voltammetric and amperometric determination of selected catecholamine metabolites using glassy carbon paste electrode
AU - Dejmkova, Hana
AU - Adamkova, Hana
AU - Barek, Jiri
AU - Zima, Jiri
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Abstract: Two methods, using glassy carbon paste electrode for the simultaneous determination homovanillic acid and vanillylmandelic acid, of two catecholamine neurotransmitter metabolites that can serve as biomarkers of several oncological diseases, were developed, based on differential pulse voltammetry and HPLC with amperometric detection. Low selectivity of the voltammetric method was limiting for the determination in urine samples; inclusion of chromatographic separation enabled the application in complex matrix. Graphical abstract: [Figure not available: see fulltext.]
AB - Abstract: Two methods, using glassy carbon paste electrode for the simultaneous determination homovanillic acid and vanillylmandelic acid, of two catecholamine neurotransmitter metabolites that can serve as biomarkers of several oncological diseases, were developed, based on differential pulse voltammetry and HPLC with amperometric detection. Low selectivity of the voltammetric method was limiting for the determination in urine samples; inclusion of chromatographic separation enabled the application in complex matrix. Graphical abstract: [Figure not available: see fulltext.]
KW - Electrochemistry
KW - High pressure liquid chromatography
KW - Homovanillic acid
KW - Vanillylmandelic acid
KW - Voltammetry
UR - http://www.scopus.com/inward/record.url?scp=85011650443&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85011650443&partnerID=8YFLogxK
U2 - 10.1007/s00706-016-1902-8
DO - 10.1007/s00706-016-1902-8
M3 - Article
AN - SCOPUS:85011650443
VL - 148
SP - 511
EP - 515
JO - Monatshefte fur Chemie
JF - Monatshefte fur Chemie
SN - 0026-9247
IS - 3
ER -