Variability of the biological activity of oxidized titanium implants

V. P. Shakhov, V. I. Vereschagin, T. S. Petrovskaya, Victor Pavlovich Ignatov, A. V. Krylatov

Research output: Contribution to journalArticlepeer-review


Oxidized titanium is a biologically inert material, but bioinertness reduces biomechanical characteristics of titanium implants. Modification of the structure of oxide surface layer of BT 5-1 titanium by increasing its thickness (by 1.7 times) and pore diameter (by 1.4 times) and by adding phosphorus, aluminum, and zinc oxides to its composition leads to radical modification of its biological characteristics. These implants acquire osteoinductive properties in in vivo systems not found in pure or oxidized BT 1-00 titanium and fairly well maintain in vitro growth of mesenchymal cells.

Original languageEnglish
Pages (from-to)475-479
Number of pages5
JournalBulletin of Experimental Biology and Medicine
Issue number4
Publication statusPublished - Feb 2012


  • Bioactivity
  • Bioinertness
  • Implant
  • Mesenchymal stem cells
  • Titanium

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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