Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization

A. A. Bakibaev, Victoria Victorovna Shtrykova, S. N. Vostretsov

Research output: Contribution to journalArticle

Abstract

A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.

Original languageEnglish
Pages (from-to)457-459
Number of pages3
JournalRussian Journal of Organic Chemistry
Volume33
Issue number4
Publication statusPublished - Apr 1997

Fingerprint

Cyclization
Urea
Heating
sulfuric acid
benzohydrol

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization. / Bakibaev, A. A.; Shtrykova, Victoria Victorovna; Vostretsov, S. N.

In: Russian Journal of Organic Chemistry, Vol. 33, No. 4, 04.1997, p. 457-459.

Research output: Contribution to journalArticle

@article{a8d4fa4de80e484cb3ce3886037f4e65,
title = "Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization",
abstract = "A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.",
author = "Bakibaev, {A. A.} and Shtrykova, {Victoria Victorovna} and Vostretsov, {S. N.}",
year = "1997",
month = "4",
language = "English",
volume = "33",
pages = "457--459",
journal = "Russian Journal of Organic Chemistry",
issn = "1070-4280",
publisher = "Maik Nauka-Interperiodica Publishing",
number = "4",

}

TY - JOUR

T1 - Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization

AU - Bakibaev, A. A.

AU - Shtrykova, Victoria Victorovna

AU - Vostretsov, S. N.

PY - 1997/4

Y1 - 1997/4

N2 - A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.

AB - A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.

UR - http://www.scopus.com/inward/record.url?scp=0031321349&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031321349&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0031321349

VL - 33

SP - 457

EP - 459

JO - Russian Journal of Organic Chemistry

JF - Russian Journal of Organic Chemistry

SN - 1070-4280

IS - 4

ER -