A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.
|Number of pages||3|
|Journal||Russian Journal of Organic Chemistry|
|Publication status||Published - Apr 1997|
ASJC Scopus subject areas
- Organic Chemistry