Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization

A. A. Bakibaev, Victoria Victorovna Shtrykova, S. N. Vostretsov

Research output: Contribution to journalArticle

Abstract

A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.

Original languageEnglish
Pages (from-to)457-459
Number of pages3
JournalRussian Journal of Organic Chemistry
Volume33
Issue number4
Publication statusPublished - Apr 1997

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ASJC Scopus subject areas

  • Organic Chemistry

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