Upconversion nanoparticles and their hybrid assemblies for biomedical applications

Abstract

The progress in the design of hybrid photoluminescent assemblies based on upconversion nanoparticles (UCNPs) meant for biomedical applications is analyzed. The key approaches to the synthesis of bright UCNPs and their surface modification, including encapsulation into hydrophilic shells and providing with therapeutic and targeting agents, are described. The range of potential applications of UCNPs in analytical biochemistry, biomedical diagnostics and therapy of cancer and infectious diseases is considered.

Original language	English
Pages (from-to)	1277-1296
Number of pages	20
Journal	Russian Chemical Reviews
Volume	85
Issue number	12
DOIs	https://doi.org/10.1070/RCR4663
Publication status	Published - 2016
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

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10.1070/RCR4663

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title = "Upconversion nanoparticles and their hybrid assemblies for biomedical applications",

abstract = "The progress in the design of hybrid photoluminescent assemblies based on upconversion nanoparticles (UCNPs) meant for biomedical applications is analyzed. The key approaches to the synthesis of bright UCNPs and their surface modification, including encapsulation into hydrophilic shells and providing with therapeutic and targeting agents, are described. The range of potential applications of UCNPs in analytical biochemistry, biomedical diagnostics and therapy of cancer and infectious diseases is considered.",

author = "Grebenik, {Ekaterina A.} and Kostyuk, {Alexey B.} and Deyev, {Sergey M.}",

year = "2016",

doi = "10.1070/RCR4663",

language = "English",

volume = "85",

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journal = "Russian Chemical Reviews",

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AB - The progress in the design of hybrid photoluminescent assemblies based on upconversion nanoparticles (UCNPs) meant for biomedical applications is analyzed. The key approaches to the synthesis of bright UCNPs and their surface modification, including encapsulation into hydrophilic shells and providing with therapeutic and targeting agents, are described. The range of potential applications of UCNPs in analytical biochemistry, biomedical diagnostics and therapy of cancer and infectious diseases is considered.

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