Abstract
The reaction of o-ethynylbenzoic acids hydrazides with base has been studied. In the presence of a strong donor substituent (1,5-dimethylpyrazol-4- yl) it has been found that an unusual cyclization route occurs to give the corresponding benzopyridazinone instead of the expected isoindolinone.
| Original language | English |
|---|---|
| Pages (from-to) | 55-58 |
| Number of pages | 4 |
| Journal | Chemistry of Heterocyclic Compounds |
| Volume | 45 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Jan 2009 |
| Externally published | Yes |
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Keywords
- Arylacetylenes
- Benzopyridazinones
- Cross coupling
- Ethynylbenzoic acids esters
- Heterocyclization
- Isoindolinones
- Reactions with hydrazine
ASJC Scopus subject areas
- Organic Chemistry
Cite this
Unexpected cyclization route for o-ethynylbenzoic acids hydrazides in the presence of base. / Vasilevsky, S. F.; Mikhailovskaya, T. F.
In: Chemistry of Heterocyclic Compounds, Vol. 45, No. 1, 01.01.2009, p. 55-58.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Unexpected cyclization route for o-ethynylbenzoic acids hydrazides in the presence of base
AU - Vasilevsky, S. F.
AU - Mikhailovskaya, T. F.
PY - 2009/1/1
Y1 - 2009/1/1
N2 - The reaction of o-ethynylbenzoic acids hydrazides with base has been studied. In the presence of a strong donor substituent (1,5-dimethylpyrazol-4- yl) it has been found that an unusual cyclization route occurs to give the corresponding benzopyridazinone instead of the expected isoindolinone.
AB - The reaction of o-ethynylbenzoic acids hydrazides with base has been studied. In the presence of a strong donor substituent (1,5-dimethylpyrazol-4- yl) it has been found that an unusual cyclization route occurs to give the corresponding benzopyridazinone instead of the expected isoindolinone.
KW - Arylacetylenes
KW - Benzopyridazinones
KW - Cross coupling
KW - Ethynylbenzoic acids esters
KW - Heterocyclization
KW - Isoindolinones
KW - Reactions with hydrazine
UR - http://www.scopus.com/inward/record.url?scp=67349257873&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67349257873&partnerID=8YFLogxK
U2 - 10.1007/s10593-009-0225-7
DO - 10.1007/s10593-009-0225-7
M3 - Article
VL - 45
SP - 55
EP - 58
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
SN - 0009-3122
IS - 1
ER -