Ultrastructure of Rat Kidneys after Intravenous Administration of Modified Magnetite Nanoparticles

I. V. Mil’to, I. V. Sukhodolo, V. V. Ivanova, M. S. Yusubov

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.

Original languageEnglish
Pages (from-to)218-222
Number of pages5
JournalBulletin of Experimental Biology and Medicine
Volume164
Issue number2
DOIs
Publication statusPublished - 1 Dec 2017

Fingerprint

Magnetite Nanoparticles
Nanospheres
Macrophages
Liposomes
Intravenous Administration
Rats
Kidney
Podocytes
Mesangial Cells
Chitosan
Transmission Electron Microscopy
Connective Tissue
Nanoparticles
Suspensions
Tissue
Transmission electron microscopy
Lipids

Keywords

  • magnetic liposomes
  • magnetic nanospheres
  • magnetite nanoparticles

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Ultrastructure of Rat Kidneys after Intravenous Administration of Modified Magnetite Nanoparticles. / Mil’to, I. V.; Sukhodolo, I. V.; Ivanova, V. V.; Yusubov, M. S.

In: Bulletin of Experimental Biology and Medicine, Vol. 164, No. 2, 01.12.2017, p. 218-222.

Research output: Contribution to journalArticle

@article{3a3be3360d514616aa94a714539a1779,
title = "Ultrastructure of Rat Kidneys after Intravenous Administration of Modified Magnetite Nanoparticles",
abstract = "The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.",
keywords = "magnetic liposomes, magnetic nanospheres, magnetite nanoparticles",
author = "Mil’to, {I. V.} and Sukhodolo, {I. V.} and Ivanova, {V. V.} and Yusubov, {M. S.}",
year = "2017",
month = "12",
day = "1",
doi = "10.1007/s10517-017-3962-0",
language = "English",
volume = "164",
pages = "218--222",
journal = "Bulletin of Experimental Biology and Medicine",
issn = "0007-4888",
publisher = "Springer New York",
number = "2",

}

TY - JOUR

T1 - Ultrastructure of Rat Kidneys after Intravenous Administration of Modified Magnetite Nanoparticles

AU - Mil’to, I. V.

AU - Sukhodolo, I. V.

AU - Ivanova, V. V.

AU - Yusubov, M. S.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.

AB - The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.

KW - magnetic liposomes

KW - magnetic nanospheres

KW - magnetite nanoparticles

UR - http://www.scopus.com/inward/record.url?scp=85034965316&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85034965316&partnerID=8YFLogxK

U2 - 10.1007/s10517-017-3962-0

DO - 10.1007/s10517-017-3962-0

M3 - Article

VL - 164

SP - 218

EP - 222

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 2

ER -