Ultrastructure of Rat Kidneys after Intravenous Administration of Modified Magnetite Nanoparticles

I. V. Mil’to, I. V. Sukhodolo, V. V. Ivanova, M. S. Yusubov

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.

Original languageEnglish
Pages (from-to)218-222
Number of pages5
JournalBulletin of Experimental Biology and Medicine
Volume164
Issue number2
DOIs
Publication statusPublished - 1 Dec 2017

Keywords

  • magnetic liposomes
  • magnetic nanospheres
  • magnetite nanoparticles

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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