Abstract
Tri(1-naphthyl)phosphine (Np3P) has been easily prepared in 34% yield from red phosphorus and 1-bromonaphthalene in the superbasic system t-BuONa/DMSO. The expedient procedures for the synthesis of aryl acetylenes by Sonogashira coupling of aryl iodides with terminal alkynes using Np3P as a ligand have been developed. For the first time, it is found that the reaction with compounds containing electron-donating substituents preferably affords buta-1,3-diynes.
Original language | English |
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Article number | e21443 |
Journal | Heteroatom Chemistry |
Volume | 29 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Jul 2018 |
Externally published | Yes |
Keywords
- 1-bromonaphthalene
- Sonogashira coupling
- superbasic system
- tri(1-naphthyl)phosphine
ASJC Scopus subject areas
- Chemistry(all)