Single-photon emission tomoscintigraphy (SPECT) was used to assess local effects of surgery in patients with monolateral cerebrovascular disorders treated by carotid endarterectomy or external carotid artery plasty. Perfusion tomoscintigraphy of the brain was carried out with 99mTc-hexamethylpropylene aminoxime (740 MBq) before and after surgery with recording 64 planar projections, 75000 pulses per position, and was followed by estimation of cerebral perfusion by H. Lassen's three-compartmental kinetic model. In patients with moderately lowered local cerebral blood flow (22-43 ml/min/100 g) and extensive regional hypoperfusion of the brain in the median cerebral artery basin before surgery a reconstructive angiosurgical treatment resulted in a most marked postoperative improvement of brain blood supply. It local cerebral blood flow were higher than 44 ml/min/100 g or lower than 18 ml/min/100 g surgery was virtually ineffective. The most marked increase of cerebral blood flow occurred after carotid endarterectomy in the carotid artery, in the anteriour cerebral artery basin on the side of operation.
|Number of pages||4|
|Journal||Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'|
|Publication status||Published - Jan 1994|
ASJC Scopus subject areas
- Nuclear Energy and Engineering