Three-year experience with fast neutron irradiation using Y-120 cyclotron

B. N. Zyryanov, L. I. Musabayeva, V. A. Lisin, K. A. Lavrenkov, Z. D. Kitsmanyuk, O. D. Shumayeva, M. V. Podoplekin, V. A. Novikov, A. I. Gorbatenko

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    Abstract

    The paper discusses the results of treatment of 128 patients with head and neck cancer in whom fast neutrons (Y-120; ~6.2 MeV) were used as a single procedure or in combination with surgery. Tumors of different histomorphologic structure displayed unequal sensitivity to fast neutrons. Mean disease-free survival in patients with complete regression of tumor was 24 months following neutron therapy alone, 18.5 months after combined neutron-photon treatment and 5.5 months only in controls. Relapse rates were 20 and 15% in patients with pre- and postoperative neutron treatment, respectively, as compared to 52% in controls.

    Original languageEnglish
    Pages (from-to)1341-1345
    Number of pages5
    JournalVoprosy Onkologii
    Volume35
    Issue number11
    Publication statusPublished - 1989

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    ASJC Scopus subject areas

    • Oncology

    Cite this

    Zyryanov, B. N., Musabayeva, L. I., Lisin, V. A., Lavrenkov, K. A., Kitsmanyuk, Z. D., Shumayeva, O. D., ... Gorbatenko, A. I. (1989). Three-year experience with fast neutron irradiation using Y-120 cyclotron. Voprosy Onkologii, 35(11), 1341-1345.