Thermal interaction of biological tissue with nanoparticles heated by laser radiation

A. Y. Krainov, K. M. Moiseeva, A. V. Shapovalov

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We explore the problem of thermal interaction of nanoparticles heated by laser radiation with a biological tissue after particle flow entering the cell. The solution of the model equations is obtained numerically under the following assumptions: a single particle is located in a neighborhood exceeding the particle size; the environment surrounding the particle is water with the conventional thermal characteristics. The model equations are deduced from the particle and the environment energy conditions taking into account the heat transfer in the particle and in its environment by conduction. We also assume that at the boundary between the particle and the surrounding water the perfect thermal contact takes place. The numerical solution of the problem is carried out with the use of an implicit difference scheme and the sweep method. Two cases of the laser pulse action on a particle are considered: a single pulse and a series of pulses. The dynamics of the temperature isoline propagation is obtained at which protein denaturation occurs in the space around the metal nanoparticle in the cases when the particles are heated by a single pulse and a series of pulses. The dependence of the heating rate and the heating depth of the medium on the laser pulse repetition frequency is found.

Original languageEnglish
Title of host publicationInternational Conference on Atomic and Molecular Pulsed Lasers XII
PublisherSPIE
Volume9810
ISBN (Electronic)9781510600515
DOIs
Publication statusPublished - 2015
Externally publishedYes
EventInternational Conference on Atomic and Molecular Pulsed Lasers XII - Tomsk, Russian Federation
Duration: 13 Sep 201518 Sep 2015

Conference

ConferenceInternational Conference on Atomic and Molecular Pulsed Lasers XII
CountryRussian Federation
CityTomsk
Period13.9.1518.9.15

Fingerprint

Biological Tissue
Laser Radiation
Laser radiation
Nanoparticles
laser beams
Tissue
nanoparticles
Laser pulses
Interaction
Denaturation
Water
Metal nanoparticles
interactions
pulses
Heating rate
Particle size
Heat transfer
Proteins
Heating
Laser

Keywords

  • dynamic destruction of the cell
  • heat exchange
  • interstitial thermal therapy
  • Laser radiation
  • nanoparticles
  • numerical simulation

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Krainov, A. Y., Moiseeva, K. M., & Shapovalov, A. V. (2015). Thermal interaction of biological tissue with nanoparticles heated by laser radiation. In International Conference on Atomic and Molecular Pulsed Lasers XII (Vol. 9810). [981020] SPIE. https://doi.org/10.1117/12.2225585

Thermal interaction of biological tissue with nanoparticles heated by laser radiation. / Krainov, A. Y.; Moiseeva, K. M.; Shapovalov, A. V.

International Conference on Atomic and Molecular Pulsed Lasers XII. Vol. 9810 SPIE, 2015. 981020.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Krainov, AY, Moiseeva, KM & Shapovalov, AV 2015, Thermal interaction of biological tissue with nanoparticles heated by laser radiation. in International Conference on Atomic and Molecular Pulsed Lasers XII. vol. 9810, 981020, SPIE, International Conference on Atomic and Molecular Pulsed Lasers XII, Tomsk, Russian Federation, 13.9.15. https://doi.org/10.1117/12.2225585
Krainov AY, Moiseeva KM, Shapovalov AV. Thermal interaction of biological tissue with nanoparticles heated by laser radiation. In International Conference on Atomic and Molecular Pulsed Lasers XII. Vol. 9810. SPIE. 2015. 981020 https://doi.org/10.1117/12.2225585
Krainov, A. Y. ; Moiseeva, K. M. ; Shapovalov, A. V. / Thermal interaction of biological tissue with nanoparticles heated by laser radiation. International Conference on Atomic and Molecular Pulsed Lasers XII. Vol. 9810 SPIE, 2015.
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