Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed)

Igor A. Schepetkin, Andrew G. Ramstead, Liliya N. Kirpotina, Jovanka M. Voyich, Mark A. Jutila, Mark T. Quinn

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Epilobium angustifolium is a medicinal plant used around the world in traditional medicine for the treatment of many disorders and ailments. Experimental studies have demonstrated that Epilobium extracts possess a broad range of pharmacological and therapeutic effects, including antioxidant, anti-proliferative, anti-inflammatory, antibacterial, and anti-aging properties. Flavonoids and ellagitannins, such as oenothein B, are among the compounds considered to be the primary biologically active components in Epilobium extracts. In this review, we focus on the biological properties and the potential clinical usefulness of oenothein B, flavonoids, and other polyphenols derived from E. angustifolium. Understanding the biochemical properties and therapeutic effects of polyphenols present in E. angustifolium extracts will benefit further development of therapeutic treatments from this plant.

Original languageEnglish
JournalPhytotherapy Research
DOIs
Publication statusAccepted/In press - 2016
Externally publishedYes

Keywords

  • Ellagitannin
  • Epilobium angustifolium
  • Oenothein B
  • Polyphenol

ASJC Scopus subject areas

  • Pharmacology

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    Schepetkin, I. A., Ramstead, A. G., Kirpotina, L. N., Voyich, J. M., Jutila, M. A., & Quinn, M. T. (Accepted/In press). Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed). Phytotherapy Research. https://doi.org/10.1002/ptr.5648