Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed)

Igor A. Schepetkin, Andrew G. Ramstead, Liliya N. Kirpotina, Jovanka M. Voyich, Mark A. Jutila, Mark T. Quinn

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Epilobium angustifolium is a medicinal plant used around the world in traditional medicine for the treatment of many disorders and ailments. Experimental studies have demonstrated that Epilobium extracts possess a broad range of pharmacological and therapeutic effects, including antioxidant, anti-proliferative, anti-inflammatory, antibacterial, and anti-aging properties. Flavonoids and ellagitannins, such as oenothein B, are among the compounds considered to be the primary biologically active components in Epilobium extracts. In this review, we focus on the biological properties and the potential clinical usefulness of oenothein B, flavonoids, and other polyphenols derived from E. angustifolium. Understanding the biochemical properties and therapeutic effects of polyphenols present in E. angustifolium extracts will benefit further development of therapeutic treatments from this plant.

Original languageEnglish
JournalPhytotherapy Research
DOIs
Publication statusAccepted/In press - 2016
Externally publishedYes

Fingerprint

Bassia scoparia
Epilobium
Polyphenols
Therapeutic Uses
Flavonoids
Hydrolyzable Tannins
Traditional Medicine
Medicinal Plants
Anti-Inflammatory Agents
Therapeutics
Antioxidants
Pharmacology
oenothein B

Keywords

  • Ellagitannin
  • Epilobium angustifolium
  • Oenothein B
  • Polyphenol

ASJC Scopus subject areas

  • Pharmacology

Cite this

Schepetkin, I. A., Ramstead, A. G., Kirpotina, L. N., Voyich, J. M., Jutila, M. A., & Quinn, M. T. (Accepted/In press). Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed). Phytotherapy Research. https://doi.org/10.1002/ptr.5648

Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed). / Schepetkin, Igor A.; Ramstead, Andrew G.; Kirpotina, Liliya N.; Voyich, Jovanka M.; Jutila, Mark A.; Quinn, Mark T.

In: Phytotherapy Research, 2016.

Research output: Contribution to journalArticle

Schepetkin, Igor A. ; Ramstead, Andrew G. ; Kirpotina, Liliya N. ; Voyich, Jovanka M. ; Jutila, Mark A. ; Quinn, Mark T. / Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed). In: Phytotherapy Research. 2016.
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