The voltammetric determination of peroxynitrite at a mercury film electrode

Elza A. Zakharova, Tatyana A. Yurmazova, Boris F. Nazarov, Gregory G. Wildgoose, Richard G. Compton

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

This report describes the direct voltammetric detection of peroxynitrite (PN, ONOO-), an important analyte in many physiological biochemical pathways, at a mercury film electrode (MFE) at alkaline pH. The voltammetric response of PN is observed as a cathodic inverted peak when the potential is swept in the oxidative direction at ca. -0.1 V vs. a Ag/AgCl/1 M KCl reference electrode. An mechanism is proposed to explain this behaviour involving the initial formation of a thin film of Hg(i) oxide on the electrode which is then oxidised by PN to form HgO in a chemical step. The HgO is then reduced back to Hg(0) at the electrode potential of interest resulting in a net cathodic current. The parameters affecting the voltammetry of PN at a MFE, including the concentration of PN (10-5-10-4 M), the effect of varying scan rate (5-100 mV s-1) and pH are investigated and the kinetics of PN decay in alkaline solutions ranging from pH 9-13 are explored electrochemically.

Original languageEnglish
Pages (from-to)394-400
Number of pages7
JournalNew Journal of Chemistry
Volume31
Issue number3
DOIs
Publication statusPublished - 12 Mar 2007

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Peroxynitrous Acid
Mercury
Electrodes
Voltammetry
Oxides
Thin films
Kinetics

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Materials Chemistry

Cite this

The voltammetric determination of peroxynitrite at a mercury film electrode. / Zakharova, Elza A.; Yurmazova, Tatyana A.; Nazarov, Boris F.; Wildgoose, Gregory G.; Compton, Richard G.

In: New Journal of Chemistry, Vol. 31, No. 3, 12.03.2007, p. 394-400.

Research output: Contribution to journalArticle

Zakharova, Elza A. ; Yurmazova, Tatyana A. ; Nazarov, Boris F. ; Wildgoose, Gregory G. ; Compton, Richard G. / The voltammetric determination of peroxynitrite at a mercury film electrode. In: New Journal of Chemistry. 2007 ; Vol. 31, No. 3. pp. 394-400.
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AU - Compton, Richard G.

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AB - This report describes the direct voltammetric detection of peroxynitrite (PN, ONOO-), an important analyte in many physiological biochemical pathways, at a mercury film electrode (MFE) at alkaline pH. The voltammetric response of PN is observed as a cathodic inverted peak when the potential is swept in the oxidative direction at ca. -0.1 V vs. a Ag/AgCl/1 M KCl reference electrode. An mechanism is proposed to explain this behaviour involving the initial formation of a thin film of Hg(i) oxide on the electrode which is then oxidised by PN to form HgO in a chemical step. The HgO is then reduced back to Hg(0) at the electrode potential of interest resulting in a net cathodic current. The parameters affecting the voltammetry of PN at a MFE, including the concentration of PN (10-5-10-4 M), the effect of varying scan rate (5-100 mV s-1) and pH are investigated and the kinetics of PN decay in alkaline solutions ranging from pH 9-13 are explored electrochemically.

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