The use of silver solid amalgam working electrode for determination of nitrophenols by HPLC with electrochemical detection

Ales Danhel, Kwok Keung Shin, Bogdan Yosypchuk, Jiri Barek, Karolina Peckova, Vlastimil Vyskocil

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The use of a silver solid amalgam working electrode for HPLC with electrochemical detection has been investigated. The thin-layer and wall-jet detectors based on this electrode were constructed and applied for the determination of a mixture of nitrophenols. The optimal separation and detection conditions for the determination of 2-nitrophenol, 4-nitrophenol, 2,4-dinitrophenol and 2-methoxy-5-nitrophenol in mixture were found using RP-HPLC at Nova-Pack C18 column and amperometric detection with the above mentioned detectors. It has been proved that the silver solid amalgam electrode is a suitable working electrode for HPLC-ED and provides sufficient sensitivity for determination of tested nitrophenols.

Original languageEnglish
Pages (from-to)303-308
Number of pages6
Issue number3-5
Publication statusPublished - 1 Feb 2009
Externally publishedYes



  • Amperometric detection
  • HPLC
  • Nitrophenols
  • Plant growth regulators
  • Silver solid amalgam
  • Thin-layer
  • Wall-jet

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry

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