Abstract
The Na+/H+-exchange inhibitor aethylisopropylamyloride was found to enhance the membrane resistance, the AP duration, and the duration of the guinea pig ureter's smooth muscle contraction. Tetraethylammonium and incubation in the Ca-free EG-TA-containing solution eliminated the activating effect of this inhibitor. Gramycidin A shortens the AP plateau. The Na+/H+-exchange mechanism seems to act under normal conditions. Alterations occurring in electrical and contractile activities of smooth muscle under the effect of the Na+/H+-exchange seem to result from the changes in the membrane Ca-dependent potassium conductivity.
| Original language | Russian |
|---|---|
| Pages (from-to) | 68-75 |
| Number of pages | 8 |
| Journal | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk |
| Volume | 86 |
| Issue number | 1 |
| Publication status | Published - Jan 2000 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Physiology
Cite this
Rol' natrii-protonnogo obmena v reguliatsii élektricheskoi i sokratitel'noi aktivnosti gladkikh myshts. / Baskakov, M. B.; Kovalev, I. V.; Kapilevich, L. V.; Medvedev, M. A.
In: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk, Vol. 86, No. 1, 01.2000, p. 68-75.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rol' natrii-protonnogo obmena v reguliatsii élektricheskoi i sokratitel'noi aktivnosti gladkikh myshts.
AU - Baskakov, M. B.
AU - Kovalev, I. V.
AU - Kapilevich, L. V.
AU - Medvedev, M. A.
PY - 2000/1
Y1 - 2000/1
N2 - The Na+/H+-exchange inhibitor aethylisopropylamyloride was found to enhance the membrane resistance, the AP duration, and the duration of the guinea pig ureter's smooth muscle contraction. Tetraethylammonium and incubation in the Ca-free EG-TA-containing solution eliminated the activating effect of this inhibitor. Gramycidin A shortens the AP plateau. The Na+/H+-exchange mechanism seems to act under normal conditions. Alterations occurring in electrical and contractile activities of smooth muscle under the effect of the Na+/H+-exchange seem to result from the changes in the membrane Ca-dependent potassium conductivity.
AB - The Na+/H+-exchange inhibitor aethylisopropylamyloride was found to enhance the membrane resistance, the AP duration, and the duration of the guinea pig ureter's smooth muscle contraction. Tetraethylammonium and incubation in the Ca-free EG-TA-containing solution eliminated the activating effect of this inhibitor. Gramycidin A shortens the AP plateau. The Na+/H+-exchange mechanism seems to act under normal conditions. Alterations occurring in electrical and contractile activities of smooth muscle under the effect of the Na+/H+-exchange seem to result from the changes in the membrane Ca-dependent potassium conductivity.
UR - http://www.scopus.com/inward/record.url?scp=17144466240&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=17144466240&partnerID=8YFLogxK
M3 - Статья
C2 - 10740839
AN - SCOPUS:17144466240
VL - 86
SP - 68
EP - 75
JO - Fiziologicheskii Zhurnal Imeni I.M. Sechenova
JF - Fiziologicheskii Zhurnal Imeni I.M. Sechenova
SN - 0869-8139
IS - 1
ER -