The role of intracellular Ca2+ pool in sodium nitroprusside-induced relaxation of rat aorta smooth muscle cells

I. V. Kovalev, M. B. Baskakov, L. V. Kapilevich, M. A. Medvedev, A. A. Panov, A. G. Popov

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

A relaxation effect of sodium nitroprusside on smooth muscle cells of rat aorta due to intracellular Ca2+-store refilling is demonstrated using the double sucrose gap technique. It is suggested that sodium nitroprusside-induced repolarization of the smooth muscle cell membrane is associated with inhibition of Ca permeability and/or Ca-dependent K+ permeability of the plasma membrane.

Original languageEnglish
Pages (from-to)160-162
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume127
Issue number2
DOIs
Publication statusPublished - Feb 1999

Keywords

  • Ca ions
  • Smooth muscle cells
  • Sodium nitroprusside

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'The role of intracellular Ca<sup>2+</sup> pool in sodium nitroprusside-induced relaxation of rat aorta smooth muscle cells'. Together they form a unique fingerprint.

Cite this