Abstract
Adaptation prevents epinephrine-induced arrhythmias in rats, the effect being abolished by naloxone, a μ-receptor antagonist, but not by the δ-receptor antagonist naltrindole. Methylnaltrexone, a blocker of peripheral μ-receptors, weakens the effect of adaptation without eliminating it completely. Central and peripheral μ-receptors may play a key role in the antiarrhythmic effect of adaptation.
| Original language | English |
|---|---|
| Pages (from-to) | 979-981 |
| Number of pages | 3 |
| Journal | Bulletin of Experimental Biology and Medicine |
| Volume | 122 |
| Issue number | 10 |
| Publication status | Published - Oct 1996 |
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Keywords
- μ- and δ-opiate receptors
- Adaptation
- Arrhythmias
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
The role of central and peripheral μ- and δ-opiate receptors in mediating the antiarrhythmic effect of adaptation. / Lishmanov, Yu B.; Maslov, L. N.; Uskina, E. V.; Krylatov, A. V.
In: Bulletin of Experimental Biology and Medicine, Vol. 122, No. 10, 10.1996, p. 979-981.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The role of central and peripheral μ- and δ-opiate receptors in mediating the antiarrhythmic effect of adaptation
AU - Lishmanov, Yu B.
AU - Maslov, L. N.
AU - Uskina, E. V.
AU - Krylatov, A. V.
PY - 1996/10
Y1 - 1996/10
N2 - Adaptation prevents epinephrine-induced arrhythmias in rats, the effect being abolished by naloxone, a μ-receptor antagonist, but not by the δ-receptor antagonist naltrindole. Methylnaltrexone, a blocker of peripheral μ-receptors, weakens the effect of adaptation without eliminating it completely. Central and peripheral μ-receptors may play a key role in the antiarrhythmic effect of adaptation.
AB - Adaptation prevents epinephrine-induced arrhythmias in rats, the effect being abolished by naloxone, a μ-receptor antagonist, but not by the δ-receptor antagonist naltrindole. Methylnaltrexone, a blocker of peripheral μ-receptors, weakens the effect of adaptation without eliminating it completely. Central and peripheral μ-receptors may play a key role in the antiarrhythmic effect of adaptation.
KW - μ- and δ-opiate receptors
KW - Adaptation
KW - Arrhythmias
UR - http://www.scopus.com/inward/record.url?scp=26944465842&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=26944465842&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:26944465842
VL - 122
SP - 979
EP - 981
JO - Bulletin of Experimental Biology and Medicine
JF - Bulletin of Experimental Biology and Medicine
SN - 0007-4888
IS - 10
ER -