Abstract
An efficient Pd-catalyzed arylation reaction of challenging acyclic olefins, in the presence of an organic ligand, has been disclosed. Commercially available cheap pyridine-based ligands are able to promote good to excellent yields for poorly efficient Heck-Matsuda arylation reactions of several allylic alcohols. A wide range of electronically different arenediazonium salts bearing either electron-releasing or withdrawing groups have been used allowing the synthesis of a range of β-aryl-methoxy-lactols. The catalytic system has been optimised, along with the reaction conditions, in order to achieve remarkable yields in less than 1 h.
| Original language | English |
|---|---|
| Pages (from-to) | 8855-8862 |
| Number of pages | 8 |
| Journal | New Journal of Chemistry |
| Volume | 40 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2016 |
Fingerprint
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
- Materials Chemistry
Cite this
The promoting effect of pyridine ligands in the Pd-catalysed Heck-Matsuda reaction. / Khodja, Walid; Leclair, Alexandre; Rull-Barrull, Jordi; Zammattio, Françoise; Kutonova, Ksenia V.; Trusova, Marina E.; Felpin, François Xavier; Rodriguez-Zubiri, Mireia.
In: New Journal of Chemistry, Vol. 40, No. 10, 2016, p. 8855-8862.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The promoting effect of pyridine ligands in the Pd-catalysed Heck-Matsuda reaction
AU - Khodja, Walid
AU - Leclair, Alexandre
AU - Rull-Barrull, Jordi
AU - Zammattio, Françoise
AU - Kutonova, Ksenia V.
AU - Trusova, Marina E.
AU - Felpin, François Xavier
AU - Rodriguez-Zubiri, Mireia
PY - 2016
Y1 - 2016
N2 - An efficient Pd-catalyzed arylation reaction of challenging acyclic olefins, in the presence of an organic ligand, has been disclosed. Commercially available cheap pyridine-based ligands are able to promote good to excellent yields for poorly efficient Heck-Matsuda arylation reactions of several allylic alcohols. A wide range of electronically different arenediazonium salts bearing either electron-releasing or withdrawing groups have been used allowing the synthesis of a range of β-aryl-methoxy-lactols. The catalytic system has been optimised, along with the reaction conditions, in order to achieve remarkable yields in less than 1 h.
AB - An efficient Pd-catalyzed arylation reaction of challenging acyclic olefins, in the presence of an organic ligand, has been disclosed. Commercially available cheap pyridine-based ligands are able to promote good to excellent yields for poorly efficient Heck-Matsuda arylation reactions of several allylic alcohols. A wide range of electronically different arenediazonium salts bearing either electron-releasing or withdrawing groups have been used allowing the synthesis of a range of β-aryl-methoxy-lactols. The catalytic system has been optimised, along with the reaction conditions, in order to achieve remarkable yields in less than 1 h.
UR - http://www.scopus.com/inward/record.url?scp=84989831314&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84989831314&partnerID=8YFLogxK
U2 - 10.1039/c6nj01717g
DO - 10.1039/c6nj01717g
M3 - Article
AN - SCOPUS:84989831314
VL - 40
SP - 8855
EP - 8862
JO - New Journal of Chemistry
JF - New Journal of Chemistry
SN - 1144-0546
IS - 10
ER -