TY - JOUR
T1 - The promoting effect of pyridine ligands in the Pd-catalysed Heck-Matsuda reaction
AU - Khodja, Walid
AU - Leclair, Alexandre
AU - Rull-Barrull, Jordi
AU - Zammattio, Françoise
AU - Kutonova, Ksenia V.
AU - Trusova, Marina E.
AU - Felpin, François Xavier
AU - Rodriguez-Zubiri, Mireia
PY - 2016
Y1 - 2016
N2 - An efficient Pd-catalyzed arylation reaction of challenging acyclic olefins, in the presence of an organic ligand, has been disclosed. Commercially available cheap pyridine-based ligands are able to promote good to excellent yields for poorly efficient Heck-Matsuda arylation reactions of several allylic alcohols. A wide range of electronically different arenediazonium salts bearing either electron-releasing or withdrawing groups have been used allowing the synthesis of a range of β-aryl-methoxy-lactols. The catalytic system has been optimised, along with the reaction conditions, in order to achieve remarkable yields in less than 1 h.
AB - An efficient Pd-catalyzed arylation reaction of challenging acyclic olefins, in the presence of an organic ligand, has been disclosed. Commercially available cheap pyridine-based ligands are able to promote good to excellent yields for poorly efficient Heck-Matsuda arylation reactions of several allylic alcohols. A wide range of electronically different arenediazonium salts bearing either electron-releasing or withdrawing groups have been used allowing the synthesis of a range of β-aryl-methoxy-lactols. The catalytic system has been optimised, along with the reaction conditions, in order to achieve remarkable yields in less than 1 h.
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U2 - 10.1039/c6nj01717g
DO - 10.1039/c6nj01717g
M3 - Article
AN - SCOPUS:84989831314
VL - 40
SP - 8855
EP - 8862
JO - New Journal of Chemistry
JF - New Journal of Chemistry
SN - 1144-0546
IS - 10
ER -