Abstract
It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl2 -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.
| Original language | English |
|---|---|
| Pages (from-to) | 37 |
| Number of pages | 1 |
| Journal | Eksperimental'naya i Klinicheskaya Farmakologiya |
| Volume | 60 |
| Issue number | 1 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl2-Induced arrhythmias : Role of the autonomic nervous system. / Maslov, L. N.; Lishmanov, Yu B.; Krylatov, A. V.; Ugdyzhekova, D. S.
In: Eksperimental'naya i Klinicheskaya Farmakologiya, Vol. 60, No. 1, 1997, p. 37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl2-Induced arrhythmias
T2 - Role of the autonomic nervous system
AU - Maslov, L. N.
AU - Lishmanov, Yu B.
AU - Krylatov, A. V.
AU - Ugdyzhekova, D. S.
PY - 1997
Y1 - 1997
N2 - It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl2 -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.
AB - It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl2 -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.
UR - http://www.scopus.com/inward/record.url?scp=0346543414&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0346543414&partnerID=8YFLogxK
M3 - Article
VL - 60
SP - 37
JO - Eksperimental'naya i Klinicheskaya Farmakologiya
JF - Eksperimental'naya i Klinicheskaya Farmakologiya
SN - 0869-2092
IS - 1
ER -