The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl<sub>2</sub>-Induced arrhythmias: Role of the autonomic nervous system

Abstract

It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl₂ -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.

Original language	English
Pages (from-to)	37
Number of pages	1
Journal	Eksperimental'naya i Klinicheskaya Farmakologiya
Volume	60
Issue number	1
Publication status	Published - 1997

ASJC Scopus subject areas

Pharmacology, Toxicology and Pharmaceutics(all)

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The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl₂-Induced arrhythmias : Role of the autonomic nervous system. / Maslov, L. N.; Lishmanov, Yu B.; Krylatov, A. V.; Ugdyzhekova, D. S.

In: Eksperimental'naya i Klinicheskaya Farmakologiya, Vol. 60, No. 1, 1997, p. 37.

Research output: Contribution to journal › Article › peer-review

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