The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl2-Induced arrhythmias: Role of the autonomic nervous system

L. N. Maslov, Yu B. Lishmanov, A. V. Krylatov, D. S. Ugdyzhekova

Research output: Contribution to journalArticle


It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl2 -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.

Original languageEnglish
Pages (from-to)37
Number of pages1
JournalEksperimental'naya i Klinicheskaya Farmakologiya
Issue number1
Publication statusPublished - 1997


ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)

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