The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl<sub>2</sub>-Induced arrhythmias: Role of the autonomic nervous system

Abstract

It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl₂ -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.

Original language	English
Pages (from-to)	37
Number of pages	1
Journal	Eksperimental'naya i Klinicheskaya Farmakologiya
Volume	60
Issue number	1
Publication status	Published - 1997

ASJC Scopus subject areas

Pharmacology, Toxicology and Pharmaceutics(all)

Fingerprint Dive into the research topics of 'The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl<sub>2</sub>-Induced arrhythmias: Role of the autonomic nervous system'. Together they form a unique fingerprint.

Cite this

The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl₂-Induced arrhythmias : Role of the autonomic nervous system. / Maslov, L. N.; Lishmanov, Yu B.; Krylatov, A. V.; Ugdyzhekova, D. S.

In: Eksperimental'naya i Klinicheskaya Farmakologiya, Vol. 60, No. 1, 1997, p. 37.

Research output: Contribution to journal › Article › peer-review

@article{fd4cbcdefe7d45019f5d28f46d9229cc,

title = "The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl2-Induced arrhythmias: Role of the autonomic nervous system",

abstract = "It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl2 -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.",

author = "Maslov, {L. N.} and Lishmanov, {Yu B.} and Krylatov, {A. V.} and Ugdyzhekova, {D. S.}",

year = "1997",

language = "English",

volume = "60",

pages = "37",

journal = "Eksperimental'naya i Klinicheskaya Farmakologiya",

issn = "0869-2092",

publisher = "Izdatelstvo Meditsina",

number = "1",

}

TY - JOUR

T1 - The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl2-Induced arrhythmias

T2 - Role of the autonomic nervous system

AU - Maslov, L. N.

AU - Lishmanov, Yu B.

AU - Krylatov, A. V.

AU - Ugdyzhekova, D. S.

PY - 1997

Y1 - 1997

N2 - It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl2 -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.

AB - It was established that selective ligands of the μ-opioid receptors DAGO and DALDA exhibit antiarrhythmic activity on a model of CACl2 -induced arrhythmias when infused intravenously in a dose of 0.2 mg/kg. The autonomic nervous system does not take part in realization of the antiarrhythmic DAGO and DALDA. It is supposed that this effect of DAGO and DALDA is associated with activation of cardiac μ-opioid receptors.

UR - http://www.scopus.com/inward/record.url?scp=0346543414&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0346543414&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0346543414

VL - 60

SP - 37

JO - Eksperimental'naya i Klinicheskaya Farmakologiya

JF - Eksperimental'naya i Klinicheskaya Farmakologiya

SN - 0869-2092

IS - 1

ER -

The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl₂-Induced arrhythmias: Role of the autonomic nervous system

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint Dive into the research topics of 'The mechanisms of antiarrhythmic effect of agonists of μ-opioid receptors on a model of CaCl<sub>2</sub>-Induced arrhythmias: Role of the autonomic nervous system'. Together they form a unique fingerprint.

Cite this