Abstract
One of the most important aspects in nonwoven materials fabrication in case biodegradable scaffolds is the control of their degradation rate which must correlate with a speed of tissue regeneration. Radiation treatment based on electron beam irradiation is one of the promising methods for control over polymer degradation. The effect of nanosecond pulsed electron beam irradiation on properties of poly-L-lactic acid (PLLA) nonwoven materials produced by solution blow spinning (SBS) method was investigated. Modification of nonwoven materials was performed in electron beam accelerator with absorbed dose from 26 to 260 kGy. Properties of the nonwoven materials were examined by means of viscosity measurement, X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FTIR) spectroscopy, and scanning electron microscopy (SEM). It was shown that pulsed electron beam exposure leads to the reduction of polymer molecular weight and recrystallization. It was shown that pulsed electron beam modification of PLLA nonwoven materials changes their physical and chemical properties that allows considering this method as a potential technology for the manipulation of polymer degradation rate and fabrication of polymer materials with required properties.
| Original language | English |
|---|---|
| Pages (from-to) | 131-139 |
| Number of pages | 9 |
| Journal | BioNanoScience |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Mar 2018 |
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Keywords
- Biodegradable polymers
- Chain scission
- Degradation
- Polylactide
- Pulsed electron beam
- Scaffolds
- Solution blow spinning
ASJC Scopus subject areas
- Bioengineering
- Biomedical Engineering
Cite this
The Influence of Pulsed Electron Beam Treatment on Properties of PLLA Nonwoven Materials Produced by Solution Blow Spinning. / Kudryavtseva, V. L.; Bolbasov, E. N.; Ponomarev, D. V.; Remnev, G. E.; Tverdokhlebov, S. I.
In: BioNanoScience, Vol. 8, No. 1, 01.03.2018, p. 131-139.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Influence of Pulsed Electron Beam Treatment on Properties of PLLA Nonwoven Materials Produced by Solution Blow Spinning
AU - Kudryavtseva, V. L.
AU - Bolbasov, E. N.
AU - Ponomarev, D. V.
AU - Remnev, G. E.
AU - Tverdokhlebov, S. I.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - One of the most important aspects in nonwoven materials fabrication in case biodegradable scaffolds is the control of their degradation rate which must correlate with a speed of tissue regeneration. Radiation treatment based on electron beam irradiation is one of the promising methods for control over polymer degradation. The effect of nanosecond pulsed electron beam irradiation on properties of poly-L-lactic acid (PLLA) nonwoven materials produced by solution blow spinning (SBS) method was investigated. Modification of nonwoven materials was performed in electron beam accelerator with absorbed dose from 26 to 260 kGy. Properties of the nonwoven materials were examined by means of viscosity measurement, X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FTIR) spectroscopy, and scanning electron microscopy (SEM). It was shown that pulsed electron beam exposure leads to the reduction of polymer molecular weight and recrystallization. It was shown that pulsed electron beam modification of PLLA nonwoven materials changes their physical and chemical properties that allows considering this method as a potential technology for the manipulation of polymer degradation rate and fabrication of polymer materials with required properties.
AB - One of the most important aspects in nonwoven materials fabrication in case biodegradable scaffolds is the control of their degradation rate which must correlate with a speed of tissue regeneration. Radiation treatment based on electron beam irradiation is one of the promising methods for control over polymer degradation. The effect of nanosecond pulsed electron beam irradiation on properties of poly-L-lactic acid (PLLA) nonwoven materials produced by solution blow spinning (SBS) method was investigated. Modification of nonwoven materials was performed in electron beam accelerator with absorbed dose from 26 to 260 kGy. Properties of the nonwoven materials were examined by means of viscosity measurement, X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FTIR) spectroscopy, and scanning electron microscopy (SEM). It was shown that pulsed electron beam exposure leads to the reduction of polymer molecular weight and recrystallization. It was shown that pulsed electron beam modification of PLLA nonwoven materials changes their physical and chemical properties that allows considering this method as a potential technology for the manipulation of polymer degradation rate and fabrication of polymer materials with required properties.
KW - Biodegradable polymers
KW - Chain scission
KW - Degradation
KW - Polylactide
KW - Pulsed electron beam
KW - Scaffolds
KW - Solution blow spinning
UR - http://www.scopus.com/inward/record.url?scp=85044378199&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044378199&partnerID=8YFLogxK
U2 - 10.1007/s12668-017-0436-9
DO - 10.1007/s12668-017-0436-9
M3 - Article
VL - 8
SP - 131
EP - 139
JO - BioNanoScience
JF - BioNanoScience
SN - 2191-1630
IS - 1
ER -