A study was made of the influence of He-Ne laser radiation (λ=632.8 nm) on spontaneous chemiluminescence (CL) of human neutrophils as well as its effect on CL stimulated by calcium ionophore (A23187) and protein kinase activator (phorbol-12-myristate-13-acetate, PMA). In vitro irradiation of the blood and a neutrophil suspension activated spontaneous CL and modulated that stimulated by A23187 (1 μM) and PMA (10 nM) within the dose range from 0.01 to 6 J/cm3. The modulation effect of irradiation is a function of radiation dose and the initial value of the integral index of stimulated CL.
|Number of pages||6|
|Publication status||Published - May 1993|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging