The influence of He-Ne laser radiation on chemiluminescence of human neutrophils

I. A. Schepetkin, V. V. Udit, A. B. Karpov

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Abstract

A study was made of the influence of He-Ne laser radiation (λ=632.8 nm) on spontaneous chemiluminescence (CL) of human neutrophils as well as its effect on CL stimulated by calcium ionophore (A23187) and protein kinase activator (phorbol-12-myristate-13-acetate, PMA). In vitro irradiation of the blood and a neutrophil suspension activated spontaneous CL and modulated that stimulated by A23187 (1 μM) and PMA (10 nM) within the dose range from 0.01 to 6 J/cm3. The modulation effect of irradiation is a function of radiation dose and the initial value of the integral index of stimulated CL.

Original languageEnglish
Pages (from-to)377-382
Number of pages6
JournalRadiobiologiya
Volume33
Issue number3
Publication statusPublished - May 1993
Externally publishedYes

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ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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