Abstract
The present work demonstrates the possibility of production of personalized implants from bioresorbable polymers designed for replacement of bone defects. The stages of creating a personalized implant are described, which include the obtaining of 3D model from a computer tomogram, development of the model with respect to shape of bone fitment bore using Autodesk Meshmixer software, and 3D printing process from bioresorbable polymers. The results of bioresorbable polymer scaffolds implantation in pre-clinical tests on laboratory animals are shown. The biological properties of new bioresorbable polymers based on poly(lactic acid) were studied during their subcutaneous, intramuscular, bone and intraosseous implantation in laboratory animals. In all cases, there was a lack of a fibrous capsule formation around the bioresorbable polymer over time. Also, during the performed study, conclusions were made on osteogenesis intensity depending on the initial state of bone tissue.
Original language | English |
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Title of host publication | Physics of Cancer |
Subtitle of host publication | Interdisciplinary Problems and Clinical Applications - Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017 |
Editors | Elazar Y. Gutmanas, Oleg B. Naimark, Yurii P. Sharkeev |
Publisher | American Institute of Physics Inc. |
Volume | 1882 |
ISBN (Electronic) | 9780735415621 |
DOIs | |
Publication status | Published - 28 Sep 2017 |
Event | International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017 - Tomsk, Russian Federation Duration: 23 May 2017 → 26 May 2017 |
Conference
Conference | International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017 |
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Country | Russian Federation |
City | Tomsk |
Period | 23.5.17 → 26.5.17 |
ASJC Scopus subject areas
- Physics and Astronomy(all)