Abstract
The rat aorta smooth muscles were contracted and depolarised with high potassium or phenylephrin solution which was followed by a relaxation and repolarisation after sodium nitroprusside administration. The latter effect was decreased az a combined action of phenylephrin and high potassium solution. Nitroprusside seems to act through a cGMP-dependent potassium transient activation of the smooth muscle cell membrane.
| Translated title of the contribution | The effect of sodium nitroprusside on the membrane potential and mechanical tension of the smooth-muscle cells in the rat aorta |
|---|---|
| Original language | Russian |
| Pages (from-to) | 70-76 |
| Number of pages | 7 |
| Journal | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk |
| Volume | 83 |
| Issue number | 7 |
| Publication status | Published - Jul 1997 |
| Externally published | Yes |
ASJC Scopus subject areas
- Physiology
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Cite this
Kovalev, I. V., Baskakov, M. B., Panov, A. A., Petrov, E. I., Kapilevich, L. V., & Medvedev, M. A. (1997). Vliianie nitroprussida natriia na membrannyi potentsial i mekhanicheskoe napriazhenie gladkomyshechnykh kletok aorty krysy. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk, 83(7), 70-76.