The effect of emoxipin and hystochrom on lipid peroxidation and activity of blood serum MB-phosphocreatine kinase in patients with ischemic heart disease during aorto-coronary shunting

T. V. Lasukova, E. V. Uskina, S. A. Afanas'ev, I. V. Ponomarenko, N. V. Naryzhnaya, A. M. Chernyavsk, Yu V. Lishmanov

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Comparative study of the cardioprotective effect of antioxidants emoxipin and hystochrom was conducted in patients with chronic ICD during and after operation for aorto-coronary shunting. Both drugs effectively inhibited LPO activation and reduced the reperfusion damage to the myocardium recorded according to the release of MB-PCK into the blood. The new antioxidant hystochrom proved to be more effective. Its prevalent effect is associated with its higher antioxidant activity.

Original languageEnglish
Number of pages1
JournalEksperimental'naya i Klinicheskaya Farmakologiya
Volume60
Issue number5
Publication statusPublished - 1 Jan 1997

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Phosphocreatine
Lipid Peroxidation
Myocardial Ischemia
Blood
Phosphotransferases
Antioxidants
Lipids
Serum
Reperfusion Injury
Myocardium
Chemical activation
Pharmaceutical Preparations
6-methyl-2-ethyl-3-hydroxypyridine

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

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The effect of emoxipin and hystochrom on lipid peroxidation and activity of blood serum MB-phosphocreatine kinase in patients with ischemic heart disease during aorto-coronary shunting. / Lasukova, T. V.; Uskina, E. V.; Afanas'ev, S. A.; Ponomarenko, I. V.; Naryzhnaya, N. V.; Chernyavsk, A. M.; Lishmanov, Yu V.

In: Eksperimental'naya i Klinicheskaya Farmakologiya, Vol. 60, No. 5, 01.01.1997.

Research output: Contribution to journalArticle

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AU - Uskina, E. V.

AU - Afanas'ev, S. A.

AU - Ponomarenko, I. V.

AU - Naryzhnaya, N. V.

AU - Chernyavsk, A. M.

AU - Lishmanov, Yu V.

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