The change of optical properties of the breast tissues under the influence of pharmacological agents

Abstract

The influence of vasoactive pharmacological agents (VPhA) on the spectral characteristics of the breast tissues in vivo has been studied. The effect of adrenaline and its antagonist dibazole on the character of diffuse reflection spectra of the breast registered during puncture biopsy were investigated. Adrenaline and dibazole were injected both locally, i.e. to the examined breast tissue and subcutaneously to the shoulder. The choice of this or that VPhA was caused by the functional condition of an examinee. It has been shown that the main functional units of the stroma of parenchymatous organs and their tumors responsible for the state of spectral characteristics in vivo are considered to be the vessels. The cancerous tissue has a lesser pronounced response compared to the normal one that is indicative of the functional inferiority of the tumor vessels and it is confirmed by the results of morphological examinations including the ultrastructural level. Thus, using VPhA it is possible to have an influence on characteristics of diffuse reflection spectra of the examined tissues in vivo and make diagnostics more effectively.

Original language	English
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Editors	R.R. Anderson, K.E. Bartels, L.S. Bass, C.G. Garrett
Pages	529-535
Number of pages	7
Volume	4244
DOIs	https://doi.org/10.1117/12.427837
Publication status	Published - 2001
Event	Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI - San Jose,CA, United States Duration: 20 Jun 2001 → 23 Jun 2001

Other

Other	Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI
Country	United States
City	San Jose,CA
Period	20.6.01 → 23.6.01

Keywords

Adrenaline
Breast cancer
Dibazole
Doppler
Mammary gland
Ultrasound
Vasoactive

ASJC Scopus subject areas

Electrical and Electronic Engineering
Condensed Matter Physics

Access to Document

10.1117/12.427837

Fingerprint Dive into the research topics of 'The change of optical properties of the breast tissues under the influence of pharmacological agents'. Together they form a unique fingerprint.

Cite this

Naumov, S. A., Vovk, S. M., Pushcarev, S. V., & Volovodenko, V. A. (2001). The change of optical properties of the breast tissues under the influence of pharmacological agents. In R. R. Anderson, K. E. Bartels, L. S. Bass, & C. G. Garrett (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4244, pp. 529-535) https://doi.org/10.1117/12.427837

The change of optical properties of the breast tissues under the influence of pharmacological agents. / Naumov, S. A.; Vovk, S. M.; Pushcarev, S. V.; Volovodenko, V. A.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / R.R. Anderson; K.E. Bartels; L.S. Bass; C.G. Garrett. Vol. 4244 2001. p. 529-535.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Naumov, SA, Vovk, SM, Pushcarev, SV & Volovodenko, VA 2001, The change of optical properties of the breast tissues under the influence of pharmacological agents. in RR Anderson, KE Bartels, LS Bass & CG Garrett (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4244, pp. 529-535, Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI, San Jose,CA, United States, 20.6.01. https://doi.org/10.1117/12.427837

@inproceedings{d1cabc2768e344609d62a1b9fb89c9f6,

title = "The change of optical properties of the breast tissues under the influence of pharmacological agents",

abstract = "The influence of vasoactive pharmacological agents (VPhA) on the spectral characteristics of the breast tissues in vivo has been studied. The effect of adrenaline and its antagonist dibazole on the character of diffuse reflection spectra of the breast registered during puncture biopsy were investigated. Adrenaline and dibazole were injected both locally, i.e. to the examined breast tissue and subcutaneously to the shoulder. The choice of this or that VPhA was caused by the functional condition of an examinee. It has been shown that the main functional units of the stroma of parenchymatous organs and their tumors responsible for the state of spectral characteristics in vivo are considered to be the vessels. The cancerous tissue has a lesser pronounced response compared to the normal one that is indicative of the functional inferiority of the tumor vessels and it is confirmed by the results of morphological examinations including the ultrastructural level. Thus, using VPhA it is possible to have an influence on characteristics of diffuse reflection spectra of the examined tissues in vivo and make diagnostics more effectively.",

keywords = "Adrenaline, Breast cancer, Dibazole, Doppler, Mammary gland, Ultrasound, Vasoactive",

author = "Naumov, {S. A.} and Vovk, {S. M.} and Pushcarev, {S. V.} and Volovodenko, {V. A.}",

year = "2001",

doi = "10.1117/12.427837",

language = "English",

volume = "4244",

pages = "529--535",

editor = "R.R. Anderson and K.E. Bartels and L.S. Bass and C.G. Garrett",

booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

note = "Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI ; Conference date: 20-06-2001 Through 23-06-2001",

}

TY - GEN

T1 - The change of optical properties of the breast tissues under the influence of pharmacological agents

AU - Naumov, S. A.

AU - Vovk, S. M.

AU - Pushcarev, S. V.

AU - Volovodenko, V. A.

PY - 2001

Y1 - 2001

N2 - The influence of vasoactive pharmacological agents (VPhA) on the spectral characteristics of the breast tissues in vivo has been studied. The effect of adrenaline and its antagonist dibazole on the character of diffuse reflection spectra of the breast registered during puncture biopsy were investigated. Adrenaline and dibazole were injected both locally, i.e. to the examined breast tissue and subcutaneously to the shoulder. The choice of this or that VPhA was caused by the functional condition of an examinee. It has been shown that the main functional units of the stroma of parenchymatous organs and their tumors responsible for the state of spectral characteristics in vivo are considered to be the vessels. The cancerous tissue has a lesser pronounced response compared to the normal one that is indicative of the functional inferiority of the tumor vessels and it is confirmed by the results of morphological examinations including the ultrastructural level. Thus, using VPhA it is possible to have an influence on characteristics of diffuse reflection spectra of the examined tissues in vivo and make diagnostics more effectively.

AB - The influence of vasoactive pharmacological agents (VPhA) on the spectral characteristics of the breast tissues in vivo has been studied. The effect of adrenaline and its antagonist dibazole on the character of diffuse reflection spectra of the breast registered during puncture biopsy were investigated. Adrenaline and dibazole were injected both locally, i.e. to the examined breast tissue and subcutaneously to the shoulder. The choice of this or that VPhA was caused by the functional condition of an examinee. It has been shown that the main functional units of the stroma of parenchymatous organs and their tumors responsible for the state of spectral characteristics in vivo are considered to be the vessels. The cancerous tissue has a lesser pronounced response compared to the normal one that is indicative of the functional inferiority of the tumor vessels and it is confirmed by the results of morphological examinations including the ultrastructural level. Thus, using VPhA it is possible to have an influence on characteristics of diffuse reflection spectra of the examined tissues in vivo and make diagnostics more effectively.

KW - Adrenaline

KW - Breast cancer

KW - Dibazole

KW - Doppler

KW - Mammary gland

KW - Ultrasound

KW - Vasoactive

UR - http://www.scopus.com/inward/record.url?scp=0034936828&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034936828&partnerID=8YFLogxK

U2 - 10.1117/12.427837

DO - 10.1117/12.427837

M3 - Conference contribution

AN - SCOPUS:0034936828

VL - 4244

SP - 529

EP - 535

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Anderson, R.R.

A2 - Bartels, K.E.

A2 - Bass, L.S.

A2 - Garrett, C.G.

T2 - Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI

Y2 - 20 June 2001 through 23 June 2001

ER -