The biomaterial surface nanoscaled electrical potential promotes osteogenesis of the stromal cell

Yuri Dekhtyar, Igor Khlusov, Yurii Sharkeev, Nataliya Polyaka, Vladimir Pichugin, Marina Khlusova, Fjodor Tjulkin, Viktorija Vendinya, Elena Legostaeva, Larisa Litvinova

Research School of High-Energy Physics

Research output: Contribution to journal › Conference article › peer-review

Abstract

The calcium phosphate coating was provided onto the titanium substrate because of the nanoarc coatings technology. Both surface morphology and electrical charge of the coating were measured at the nano/micro-scaled lateral resolution. The negative electrical potential was typical for sockets, however the positive one to the peaks of the roughness. The cells were mainly attached at the negatively charged sockets. The cells expressed both osteocalcin and alkaline phosphatase that are the osteoblastic molecular markers.

Original language	English
Pages (from-to)	139-142
Number of pages	4
Journal	IFMBE Proceedings
Volume	68
Issue number	3
DOIs	https://doi.org/10.1007/978-981-10-9023-3_25
Publication status	Published - 1 Jan 2019
Event	World Congress on Medical Physics and Biomedical Engineering, WC 2018 - Prague, Czech Republic Duration: 3 Jun 2018 → 8 Jun 2018

Keywords

Human mesenchymal cells
Oeteogsteogenesis
Surface electrical potential
Surface morphology

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

Access to Document

10.1007/978-981-10-9023-3_25

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The biomaterial surface nanoscaled electrical potential promotes osteogenesis of the stromal cell. / Dekhtyar, Yuri; Khlusov, Igor ; Sharkeev, Yurii; Polyaka, Nataliya; Pichugin, Vladimir; Khlusova, Marina; Tjulkin, Fjodor; Vendinya, Viktorija; Legostaeva, Elena; Litvinova, Larisa.

In: IFMBE Proceedings, Vol. 68, No. 3, 01.01.2019, p. 139-142.

Research output: Contribution to journal › Conference article › peer-review

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abstract = "The calcium phosphate coating was provided onto the titanium substrate because of the nanoarc coatings technology. Both surface morphology and electrical charge of the coating were measured at the nano/micro-scaled lateral resolution. The negative electrical potential was typical for sockets, however the positive one to the peaks of the roughness. The cells were mainly attached at the negatively charged sockets. The cells expressed both osteocalcin and alkaline phosphatase that are the osteoblastic molecular markers.",

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AU - Pichugin, Vladimir

AU - Khlusova, Marina

AU - Tjulkin, Fjodor

AU - Vendinya, Viktorija

AU - Legostaeva, Elena

AU - Litvinova, Larisa

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