The biomaterial surface nanoscaled electrical potential promotes osteogenesis of the stromal cell

Yuri Dekhtyar, Igor Khlusov, Yurii Sharkeev, Nataliya Polyaka, Vladimir Pichugin, Marina Khlusova, Fjodor Tjulkin, Viktorija Vendinya, Elena Legostaeva, Larisa Litvinova

Research output: Contribution to journalConference article

Abstract

The calcium phosphate coating was provided onto the titanium substrate because of the nanoarc coatings technology. Both surface morphology and electrical charge of the coating were measured at the nano/micro-scaled lateral resolution. The negative electrical potential was typical for sockets, however the positive one to the peaks of the roughness. The cells were mainly attached at the negatively charged sockets. The cells expressed both osteocalcin and alkaline phosphatase that are the osteoblastic molecular markers.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalIFMBE Proceedings
Volume68
Issue number3
DOIs
Publication statusPublished - 1 Jan 2019
EventWorld Congress on Medical Physics and Biomedical Engineering, WC 2018 - Prague, Czech Republic
Duration: 3 Jun 20188 Jun 2018

Fingerprint

Biocompatible Materials
Biomaterials
Phosphate coatings
Coatings
Phosphatases
Calcium phosphate
Surface morphology
Titanium
Surface roughness
Osteocalcin
Alkaline Phosphatase
Substrates

Keywords

  • Human mesenchymal cells
  • Oeteogsteogenesis
  • Surface electrical potential
  • Surface morphology

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

Cite this

The biomaterial surface nanoscaled electrical potential promotes osteogenesis of the stromal cell. / Dekhtyar, Yuri; Khlusov, Igor; Sharkeev, Yurii; Polyaka, Nataliya; Pichugin, Vladimir; Khlusova, Marina; Tjulkin, Fjodor; Vendinya, Viktorija; Legostaeva, Elena; Litvinova, Larisa.

In: IFMBE Proceedings, Vol. 68, No. 3, 01.01.2019, p. 139-142.

Research output: Contribution to journalConference article

Dekhtyar, Y, Khlusov, I, Sharkeev, Y, Polyaka, N, Pichugin, V, Khlusova, M, Tjulkin, F, Vendinya, V, Legostaeva, E & Litvinova, L 2019, 'The biomaterial surface nanoscaled electrical potential promotes osteogenesis of the stromal cell', IFMBE Proceedings, vol. 68, no. 3, pp. 139-142. https://doi.org/10.1007/978-981-10-9023-3_25
Dekhtyar, Yuri ; Khlusov, Igor ; Sharkeev, Yurii ; Polyaka, Nataliya ; Pichugin, Vladimir ; Khlusova, Marina ; Tjulkin, Fjodor ; Vendinya, Viktorija ; Legostaeva, Elena ; Litvinova, Larisa. / The biomaterial surface nanoscaled electrical potential promotes osteogenesis of the stromal cell. In: IFMBE Proceedings. 2019 ; Vol. 68, No. 3. pp. 139-142.
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