The biomaterial surface nanoscaled electrical potential promotes osteogenesis of the stromal cell

Yuri Dekhtyar, Igor Khlusov, Yurii Sharkeev, Nataliya Polyaka, Vladimir Pichugin, Marina Khlusova, Fjodor Tjulkin, Viktorija Vendinya, Elena Legostaeva, Larisa Litvinova

Research output: Contribution to journalConference article


The calcium phosphate coating was provided onto the titanium substrate because of the nanoarc coatings technology. Both surface morphology and electrical charge of the coating were measured at the nano/micro-scaled lateral resolution. The negative electrical potential was typical for sockets, however the positive one to the peaks of the roughness. The cells were mainly attached at the negatively charged sockets. The cells expressed both osteocalcin and alkaline phosphatase that are the osteoblastic molecular markers.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalIFMBE Proceedings
Issue number3
Publication statusPublished - 1 Jan 2019
EventWorld Congress on Medical Physics and Biomedical Engineering, WC 2018 - Prague, Czech Republic
Duration: 3 Jun 20188 Jun 2018



  • Human mesenchymal cells
  • Oeteogsteogenesis
  • Surface electrical potential
  • Surface morphology

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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