Abstract
The importance of single photon emission computed tomography (SPECT) with 99mTc-HMPAO for the assessment of cerebral complications of aortal coronary by-passing (ACBP) done under artificial blood circulation (AC) and working heart is investigated. 45 IHD patients were involved in the study, which patients have been surgically treated for myocardial re-vascularization. AC applied surgeries were accompanied by the cerebral flow decrease in the frontal and back lobes of the right hemisphere. Patients treated with AC and Instenon and patients treated without heart stop have not demonstrated confident worsening of the brain perfusion. The cerebral perfusion changes were corresponded by the cognitive status dynamics. SPECT with 99mTc-HMPAO can be successfully applied to get quantitative evaluation of regional cerebral blood flow in ACBP patients. In such case, ACBP combined with Instenon prophylaxis or surgery at working heart prevent or significantly decrease the risk of cerebral hemodynamic disturbances and cognitive function disorders.
| Original language | English |
|---|---|
| Pages (from-to) | 28-34 |
| Number of pages | 7 |
| Journal | Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost' |
| Volume | 48 |
| Issue number | 3 |
| Publication status | Published - 2003 |
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Keywords
- Aortal coronary by-passing
- Artificial blood flow/ Neurocoegnitive dysfunction
- Cerebral perfusion
- Single photon emission computed tomography (SPECT)
ASJC Scopus subject areas
- Nuclear Energy and Engineering
Cite this
TC-99m HMPAO SPECT in the assessment of cerebral complications of coronary artery bypass surgery. / Chernov, V. I.; Efimova, Nataliya Yurievna; Efimova, I. Yu; Akhmedov, Sh D.; Podoksenov, Yu K.; Lishmanov, Yu B.
In: Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', Vol. 48, No. 3, 2003, p. 28-34.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - TC-99m HMPAO SPECT in the assessment of cerebral complications of coronary artery bypass surgery
AU - Chernov, V. I.
AU - Efimova, Nataliya Yurievna
AU - Efimova, I. Yu
AU - Akhmedov, Sh D.
AU - Podoksenov, Yu K.
AU - Lishmanov, Yu B.
PY - 2003
Y1 - 2003
N2 - The importance of single photon emission computed tomography (SPECT) with 99mTc-HMPAO for the assessment of cerebral complications of aortal coronary by-passing (ACBP) done under artificial blood circulation (AC) and working heart is investigated. 45 IHD patients were involved in the study, which patients have been surgically treated for myocardial re-vascularization. AC applied surgeries were accompanied by the cerebral flow decrease in the frontal and back lobes of the right hemisphere. Patients treated with AC and Instenon and patients treated without heart stop have not demonstrated confident worsening of the brain perfusion. The cerebral perfusion changes were corresponded by the cognitive status dynamics. SPECT with 99mTc-HMPAO can be successfully applied to get quantitative evaluation of regional cerebral blood flow in ACBP patients. In such case, ACBP combined with Instenon prophylaxis or surgery at working heart prevent or significantly decrease the risk of cerebral hemodynamic disturbances and cognitive function disorders.
AB - The importance of single photon emission computed tomography (SPECT) with 99mTc-HMPAO for the assessment of cerebral complications of aortal coronary by-passing (ACBP) done under artificial blood circulation (AC) and working heart is investigated. 45 IHD patients were involved in the study, which patients have been surgically treated for myocardial re-vascularization. AC applied surgeries were accompanied by the cerebral flow decrease in the frontal and back lobes of the right hemisphere. Patients treated with AC and Instenon and patients treated without heart stop have not demonstrated confident worsening of the brain perfusion. The cerebral perfusion changes were corresponded by the cognitive status dynamics. SPECT with 99mTc-HMPAO can be successfully applied to get quantitative evaluation of regional cerebral blood flow in ACBP patients. In such case, ACBP combined with Instenon prophylaxis or surgery at working heart prevent or significantly decrease the risk of cerebral hemodynamic disturbances and cognitive function disorders.
KW - Aortal coronary by-passing
KW - Artificial blood flow/ Neurocoegnitive dysfunction
KW - Cerebral perfusion
KW - Single photon emission computed tomography (SPECT)
UR - http://www.scopus.com/inward/record.url?scp=0042696968&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0042696968&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0042696968
VL - 48
SP - 28
EP - 34
JO - Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'
JF - Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'
SN - 0025-8334
IS - 3
ER -