Abstract
In this review, the authors' works published within the past 5 years devoted to the development of bifunctional hybrid nanostructures based on the targeting polypeptides and nanoparticles of various origin (quantum dots, nanogold, nanodiamonds, upconversion nanoparticles, magnetic and polymer nanoparticles) as modules that ensure visualization and various damaging effects on cancer cells are surveyed and the prospects of their application in theranostics and precision medicine have been contemplated.
Original language | English |
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Pages (from-to) | 788-803 |
Number of pages | 16 |
Journal | Molecular Biology |
Volume | 51 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Nov 2017 |
Externally published | Yes |
Keywords
- Biocomputing
- DARPins
- exotoxin A
- HER2
- imaging
- nanogold
- NIR
- photodynamic and photothermal therapies
- protein photosensitizers
- riboflavin
- scFv
- tumor xenografts
- upconverting nanophosphores
ASJC Scopus subject areas
- Biophysics
- Structural Biology