Synthesis, Structure, and Anti-Inflammatory Activity of Functionally Substituted Chalcones and Their Derivatives

O. A. Nurkenov, M. K. Ibraev, I. A. Schepetkin, A. I. Khlebnikov, T. M. Seilkhanov, A. E. Arinova, M. B. Isabaeva

Research output: Contribution to journalArticle

Abstract

Functionally substituted chalcones, pyrazolines, and flavonones have been synthesized. Their structure has been studied by means of 1H and 13C NMR spectroscopy, including COSY and HMQC experiments. Anti-inflammatory activity of the synthesized chalcones, pyrazolines, and flavonones has been evaluated.

Original languageEnglish
Pages (from-to)1360-1367
Number of pages8
JournalRussian Journal of General Chemistry
Volume89
Issue number7
DOIs
Publication statusPublished - 1 Jul 2019

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Chalcones
Anti-Inflammatory Agents
Derivatives
Nuclear magnetic resonance spectroscopy
Experiments
vitamin B 12 factor III

Keywords

  • chalcone
  • cytokine
  • flavonone
  • pyrazoline
  • substituted aromatic aldehydes
  • transcription factor NF-κB

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Synthesis, Structure, and Anti-Inflammatory Activity of Functionally Substituted Chalcones and Their Derivatives. / Nurkenov, O. A.; Ibraev, M. K.; Schepetkin, I. A.; Khlebnikov, A. I.; Seilkhanov, T. M.; Arinova, A. E.; Isabaeva, M. B.

In: Russian Journal of General Chemistry, Vol. 89, No. 7, 01.07.2019, p. 1360-1367.

Research output: Contribution to journalArticle

Nurkenov, O. A. ; Ibraev, M. K. ; Schepetkin, I. A. ; Khlebnikov, A. I. ; Seilkhanov, T. M. ; Arinova, A. E. ; Isabaeva, M. B. / Synthesis, Structure, and Anti-Inflammatory Activity of Functionally Substituted Chalcones and Their Derivatives. In: Russian Journal of General Chemistry. 2019 ; Vol. 89, No. 7. pp. 1360-1367.
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