Synthesis of unsymmetrical hetaryl-1,2-diketones

Mehman S. Yusubov, Galina A. Zholobova, Sergey F. Vasilevsky, Eugene V. Tretyakov, David W. Knight

Research output: Contribution to journal › Article

46 Citations (Scopus)

Abstract

Oxidation of the triple bond in 4-alkynylpyrazoles 2a-e and acetylenic derivatives of the crown-ethers 7a,b with PdCl2-DMSO has been carried out to give unsymmetrical hetaryl-1,2-diketones 3a-e; 8a,b. Attempts to oxidize the triple bond in 5-alkynylpyrazole 6 and alkynylpyridines 5a,b and 9 failed.

Original languageEnglish
Pages (from-to)1607-1610
Number of pages4
JournalTetrahedron
Volume58
Issue number8
DOIs
Publication statusPublished - 18 Feb 2002

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Crown Ethers
Dimethyl Sulfoxide
Derivatives
Oxidation
palladium chloride

Keywords

  • 1,2-diketones
  • Alkynes
  • Oxidation with PdCl-DMSO

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Synthesis of unsymmetrical hetaryl-1,2-diketones. / Yusubov, Mehman S.; Zholobova, Galina A.; Vasilevsky, Sergey F.; Tretyakov, Eugene V.; Knight, David W.

In: Tetrahedron, Vol. 58, No. 8, 18.02.2002, p. 1607-1610.

Research output: Contribution to journal › Article

Yusubov, MS, Zholobova, GA, Vasilevsky, SF, Tretyakov, EV & Knight, DW 2002, 'Synthesis of unsymmetrical hetaryl-1,2-diketones', Tetrahedron, vol. 58, no. 8, pp. 1607-1610. https://doi.org/10.1016/S0040-4020(02)00025-X
Yusubov MS, Zholobova GA, Vasilevsky SF, Tretyakov EV, Knight DW. Synthesis of unsymmetrical hetaryl-1,2-diketones. Tetrahedron. 2002 Feb 18;58(8):1607-1610. https://doi.org/10.1016/S0040-4020(02)00025-X
Yusubov, Mehman S. ; Zholobova, Galina A. ; Vasilevsky, Sergey F. ; Tretyakov, Eugene V. ; Knight, David W. / Synthesis of unsymmetrical hetaryl-1,2-diketones. In: Tetrahedron. 2002 ; Vol. 58, No. 8. pp. 1607-1610.
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AU - Knight, David W.

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