Synthesis of unsymmetrical hetaryl-1,2-diketones

Mehman S. Yusubov, Galina A. Zholobova, Sergey F. Vasilevsky, Eugene V. Tretyakov, David W. Knight

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)


Oxidation of the triple bond in 4-alkynylpyrazoles 2a-e and acetylenic derivatives of the crown-ethers 7a,b with PdCl2-DMSO has been carried out to give unsymmetrical hetaryl-1,2-diketones 3a-e; 8a,b. Attempts to oxidize the triple bond in 5-alkynylpyrazole 6 and alkynylpyridines 5a,b and 9 failed.

Original languageEnglish
Pages (from-to)1607-1610
Number of pages4
Issue number8
Publication statusPublished - 18 Feb 2002


  • 1,2-diketones
  • Alkynes
  • Oxidation with PdCl-DMSO

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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