Abstract
MRI and morphological investigations into internal organ tissues and tumors in rats with liver cancer PC-1 under the intraperitoneal administration of magnetite hydrosols have been performed. The absence of any toxic effect of magnetite nanoparticles at low concentrations (0.325 mg/mL) has been determined using neutrophil granulocytes. A technique for the synthesis of citrate-stabilized magnetite hydrosols by the coprecipitation of Fe2+ and Fe3+ salts is described. Their electrokinetic potential is -32 ± 2 mV at pH 6.5 ± 0.1. The size distribution of magnetite nanoparticles is obtained by dynamic light scattering. The average size of magnetite nanoparticles is 23 ± 6 nm. The absorption spectra of magnetite hydrosols have been measured. The dependence of the optical density on the concentration has also been obtained. Molar absorption coefficients of magnetite nanoparticles have been calculated at the following wavelengths: 532, 633, 660, and 785 nm.
| Original language | English |
|---|---|
| Pages (from-to) | 573-580 |
| Number of pages | 8 |
| Journal | Nanotechnologies in Russia |
| Volume | 8 |
| Issue number | 7-8 |
| DOIs | |
| Publication status | Published - Jul 2013 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Condensed Matter Physics
- Materials Science(all)
- Engineering(all)
Cite this
Synthesis of magnetite hydrosols and assessment of their impact on living systems at the cellular and tissue levels using MRI and morphological investigation. / German, S. V.; Inozemtseva, O. A.; Navolokin, N. A.; Pudovkina, E. E.; Zuev, V. V.; Volkova, E. K.; Bucharskaya, A. B.; Pleskova, S. N.; Maslyakova, G. N.; Gorin, D. A.
In: Nanotechnologies in Russia, Vol. 8, No. 7-8, 07.2013, p. 573-580.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Synthesis of magnetite hydrosols and assessment of their impact on living systems at the cellular and tissue levels using MRI and morphological investigation
AU - German, S. V.
AU - Inozemtseva, O. A.
AU - Navolokin, N. A.
AU - Pudovkina, E. E.
AU - Zuev, V. V.
AU - Volkova, E. K.
AU - Bucharskaya, A. B.
AU - Pleskova, S. N.
AU - Maslyakova, G. N.
AU - Gorin, D. A.
PY - 2013/7
Y1 - 2013/7
N2 - MRI and morphological investigations into internal organ tissues and tumors in rats with liver cancer PC-1 under the intraperitoneal administration of magnetite hydrosols have been performed. The absence of any toxic effect of magnetite nanoparticles at low concentrations (0.325 mg/mL) has been determined using neutrophil granulocytes. A technique for the synthesis of citrate-stabilized magnetite hydrosols by the coprecipitation of Fe2+ and Fe3+ salts is described. Their electrokinetic potential is -32 ± 2 mV at pH 6.5 ± 0.1. The size distribution of magnetite nanoparticles is obtained by dynamic light scattering. The average size of magnetite nanoparticles is 23 ± 6 nm. The absorption spectra of magnetite hydrosols have been measured. The dependence of the optical density on the concentration has also been obtained. Molar absorption coefficients of magnetite nanoparticles have been calculated at the following wavelengths: 532, 633, 660, and 785 nm.
AB - MRI and morphological investigations into internal organ tissues and tumors in rats with liver cancer PC-1 under the intraperitoneal administration of magnetite hydrosols have been performed. The absence of any toxic effect of magnetite nanoparticles at low concentrations (0.325 mg/mL) has been determined using neutrophil granulocytes. A technique for the synthesis of citrate-stabilized magnetite hydrosols by the coprecipitation of Fe2+ and Fe3+ salts is described. Their electrokinetic potential is -32 ± 2 mV at pH 6.5 ± 0.1. The size distribution of magnetite nanoparticles is obtained by dynamic light scattering. The average size of magnetite nanoparticles is 23 ± 6 nm. The absorption spectra of magnetite hydrosols have been measured. The dependence of the optical density on the concentration has also been obtained. Molar absorption coefficients of magnetite nanoparticles have been calculated at the following wavelengths: 532, 633, 660, and 785 nm.
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UR - http://www.scopus.com/inward/citedby.url?scp=84881508701&partnerID=8YFLogxK
U2 - 10.1134/S1995078013040034
DO - 10.1134/S1995078013040034
M3 - Article
AN - SCOPUS:84881508701
VL - 8
SP - 573
EP - 580
JO - Nanotechnologies in Russia
JF - Nanotechnologies in Russia
SN - 1995-0780
IS - 7-8
ER -