Synthesis of magnetic silica nanomarkers with controlled physicochemical properties

I. V. Zelepukin, M. P. Nikitin, V. R. Cherkasov, P. I. Nikitin, S. M. Deyev, P. V. Petrov

Research output: Contribution to journalArticlepeer-review


Magnetic markers which can be detected with an extremely high sensitivity with the method of magnetic particle quantification (MPQ) were synthesized. Using a controlled Stober reaction, a set of magnetic silica markers of different sizes and zeta potentials was obtained. The use of a carboxymethyl dextran polymer to stabilize the magnetite particles during the synthesis made it possible to substantially reduce the detection limit of the obtained construct, which opens up new opportunities for creating effective diagnostic nanoagents.

Original languageEnglish
Pages (from-to)335-337
Number of pages3
JournalDoklady Biochemistry and Biophysics
Issue number1
Publication statusPublished - 1 Sep 2016
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Chemistry(all)
  • Medicine(all)
  • Biochemistry

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