Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone

Akira Yoshimura, Anthony D. Todora, Brent J. Kastern, Steven R. Koski, Viktor V. Zhdankin

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

1,2,4-Thiadiazoles were efficiently synthesized in good yields through the oxidative dimerization of carbothioamides by using Oxone as a readily available, inexpensive, and environmentally safe oxidant. A similar reaction of phenylselenoamide led to the corresponding 1,2,4-phenylselenadiazole in high yield.

Original languageEnglish
Pages (from-to)5149-5152
Number of pages4
JournalEuropean Journal of Organic Chemistry
Volume2014
Issue number24
DOIs
Publication statusPublished - 1 Jan 2014
Externally publishedYes

Fingerprint

Thiadiazoles
Dimerization
dimerization
Oxidants
synthesis
potassium peroxymonosulfuric acid

Keywords

  • Heterocycles
  • Oxidation
  • Oxone
  • Selenium
  • Sulfur

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone. / Yoshimura, Akira; Todora, Anthony D.; Kastern, Brent J.; Koski, Steven R.; Zhdankin, Viktor V.

In: European Journal of Organic Chemistry, Vol. 2014, No. 24, 01.01.2014, p. 5149-5152.

Research output: Contribution to journalArticle

Yoshimura, Akira ; Todora, Anthony D. ; Kastern, Brent J. ; Koski, Steven R. ; Zhdankin, Viktor V. / Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone. In: European Journal of Organic Chemistry. 2014 ; Vol. 2014, No. 24. pp. 5149-5152.
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