Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations

Natalia Valerievna Varlamova, V. S. Skuridin, A. E. Sazonov, Svetlana Ivanovna Sazonova, Evgeny Alexandrovich Nesterov, L. A. Larionova

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.

Original languageEnglish
Title of host publicationKey Engineering Materials
PublisherTrans Tech Publications Ltd
Pages798-802
Number of pages5
Volume685
ISBN (Print)9783038357087
DOIs
Publication statusPublished - 2016
Event4th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2015 - Tomsk, Russian Federation
Duration: 21 Apr 201524 Apr 2015

Publication series

NameKey Engineering Materials
Volume685
ISSN (Print)10139826

Other

Other4th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2015
CountryRussian Federation
CityTomsk
Period21.4.1524.4.15

Fingerprint

Thin layer chromatography
Norfloxacin
Animals
Imaging techniques

Keywords

  • Tc'
  • Bacterial infection
  • Norfloxacin hydrochloride (NFH)
  • Radionuclide diagnostics
  • RP 'Norfloxacin
  • Technecium-99m (Tc)

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Varlamova, NV., Skuridin, V. S., Sazonov, A. E., Sazonova, SI., Nesterov, E. A., & Larionova, L. A. (2016). Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations. In Key Engineering Materials (Vol. 685, pp. 798-802). (Key Engineering Materials; Vol. 685). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.685.798

Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations. / Varlamova, Natalia Valerievna; Skuridin, V. S.; Sazonov, A. E.; Sazonova, Svetlana Ivanovna; Nesterov, Evgeny Alexandrovich; Larionova, L. A.

Key Engineering Materials. Vol. 685 Trans Tech Publications Ltd, 2016. p. 798-802 (Key Engineering Materials; Vol. 685).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Varlamova, NV, Skuridin, VS, Sazonov, AE, Sazonova, SI, Nesterov, EA & Larionova, LA 2016, Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations. in Key Engineering Materials. vol. 685, Key Engineering Materials, vol. 685, Trans Tech Publications Ltd, pp. 798-802, 4th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2015, Tomsk, Russian Federation, 21.4.15. https://doi.org/10.4028/www.scientific.net/KEM.685.798
Varlamova NV, Skuridin VS, Sazonov AE, Sazonova SI, Nesterov EA, Larionova LA. Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations. In Key Engineering Materials. Vol. 685. Trans Tech Publications Ltd. 2016. p. 798-802. (Key Engineering Materials). https://doi.org/10.4028/www.scientific.net/KEM.685.798
Varlamova, Natalia Valerievna ; Skuridin, V. S. ; Sazonov, A. E. ; Sazonova, Svetlana Ivanovna ; Nesterov, Evgeny Alexandrovich ; Larionova, L. A. / Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations. Key Engineering Materials. Vol. 685 Trans Tech Publications Ltd, 2016. pp. 798-802 (Key Engineering Materials).
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AU - Sazonova, Svetlana Ivanovna

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