Abstract
Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.
| Original language | English |
|---|---|
| Title of host publication | Key Engineering Materials |
| Publisher | Trans Tech Publications Ltd |
| Pages | 798-802 |
| Number of pages | 5 |
| Volume | 685 |
| ISBN (Print) | 9783038357087 |
| DOIs | |
| Publication status | Published - 2016 |
| Event | 4th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2015 - Tomsk, Russian Federation Duration: 21 Apr 2015 → 24 Apr 2015 |
Publication series
| Name | Key Engineering Materials |
|---|---|
| Volume | 685 |
| ISSN (Print) | 10139826 |
Other
| Other | 4th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2015 |
|---|---|
| Country | Russian Federation |
| City | Tomsk |
| Period | 21.4.15 → 24.4.15 |
Fingerprint
Keywords
- Tc'
- Bacterial infection
- Norfloxacin hydrochloride (NFH)
- Radionuclide diagnostics
- RP 'Norfloxacin
- Technecium-99m (Tc)
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering
Cite this
Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations. / Varlamova, Natalia Valerievna; Skuridin, V. S.; Sazonov, A. E.; Sazonova, Svetlana Ivanovna; Nesterov, Evgeny Alexandrovich; Larionova, L. A.
Key Engineering Materials. Vol. 685 Trans Tech Publications Ltd, 2016. p. 798-802 (Key Engineering Materials; Vol. 685).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations
AU - Varlamova, Natalia Valerievna
AU - Skuridin, V. S.
AU - Sazonov, A. E.
AU - Sazonova, Svetlana Ivanovna
AU - Nesterov, Evgeny Alexandrovich
AU - Larionova, L. A.
PY - 2016
Y1 - 2016
N2 - Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.
AB - Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.
KW - Tc'
KW - Bacterial infection
KW - Norfloxacin hydrochloride (NFH)
KW - Radionuclide diagnostics
KW - RP 'Norfloxacin
KW - Technecium-99m (Tc)
UR - http://www.scopus.com/inward/record.url?scp=84958191467&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84958191467&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.685.798
DO - 10.4028/www.scientific.net/KEM.685.798
M3 - Conference contribution
AN - SCOPUS:84958191467
SN - 9783038357087
VL - 685
T3 - Key Engineering Materials
SP - 798
EP - 802
BT - Key Engineering Materials
PB - Trans Tech Publications Ltd
ER -