Abstract
Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.
| Original language | English |
|---|---|
| Title of host publication | Key Engineering Materials |
| Publisher | Trans Tech Publications Ltd |
| Pages | 798-802 |
| Number of pages | 5 |
| Volume | 685 |
| ISBN (Print) | 9783038357087 |
| DOIs | |
| Publication status | Published - 2016 |
| Event | 4th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2015 - Tomsk, Russian Federation Duration: 21 Apr 2015 → 24 Apr 2015 |
Publication series
| Name | Key Engineering Materials |
|---|---|
| Volume | 685 |
| ISSN (Print) | 10139826 |
Other
| Other | 4th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2015 |
|---|---|
| Country | Russian Federation |
| City | Tomsk |
| Period | 21.4.15 → 24.4.15 |
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Keywords
- Tc'
- Bacterial infection
- Norfloxacin hydrochloride (NFH)
- Radionuclide diagnostics
- RP 'Norfloxacin
- Technecium-99m (Tc)
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering
Cite this
Varlamova, NV., Skuridin, V. S., Sazonov, A. E., Sazonova, SI., Nesterov, E. A., & Larionova, L. A. (2016). Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations. In Key Engineering Materials (Vol. 685, pp. 798-802). (Key Engineering Materials; Vol. 685). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.685.798