Synthesis and antioxidant evaluation of some new allobetulin esters

S. Arrous, I. Boudebouz, O. Voronova, E. Plotnikov, A. Bakibaev

Research output: Contribution to journalArticlepeer-review


A series of 3-O-haloacyl allobetulin were synthesized via acylation of allobetulin by haloacetic (trifluro,difluorochloro, trichloro, monochloro) acid in CHCl3 at 70 °C. The structure of allobetulin was modified at C-3 position, and esters 3a-d were obtained in high yields. Moreover the reactions do not need a catalyst. The structures of all synthesized compounds were confirmed by various spectroscopic methods (IR and NMR) and tested for antioxidant activity.

Original languageEnglish
Pages (from-to)1032-1037
Number of pages6
JournalRasayan Journal of Chemistry
Issue number3
Publication statusPublished - 2019


  • Allobetulin
  • Antioxidant
  • Betulin
  • Esterification
  • Haloacetic acid
  • Triterpene

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Chemical Engineering(all)
  • Energy(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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