Synthesis and antioxidant activity of some new thioglycoluril derivatives

Imene Boudebouz, Salah Arrous, Evgenii Plotnikov, Olesya Voronova, Abdigali Bakibaev

Research output: Contribution to journal › Article

Abstract

A series of S-alkylated products was prepared by alkylation of thioglycoluril with various alkylation agents, i.e. ethyl bromide, ethylene dibromide and chloroacetic acid. The synthesis performed in DMF at 60°C using sodium hydroxide as a base to give the corresponding products with significant advantages such as high conversions, short reaction time, mild reaction conditions, and low cost, simple workup with moderate to excellent yields. The structures of the synthesized compounds have been deduced from their spectral (IR, 1 H-NMR and 13 C-NMR) data. Significant antioxidant activity was observed for some members of the series.

Original languageEnglish
JournalJournal of Sulfur Chemistry
DOIs
Publication statusPublished - 1 Jan 2019

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Alkylation
Antioxidants
Ethylene Dibromide
Nuclear magnetic resonance
Derivatives
Sodium Hydroxide
Costs
chloroacetic acid

Keywords

  • alkyl halides
  • alkylation
  • antioxidant activity
  • thioamides
  • Thioglycoluril

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Synthesis and antioxidant activity of some new thioglycoluril derivatives. / Boudebouz, Imene; Arrous, Salah; Plotnikov, Evgenii; Voronova, Olesya; Bakibaev, Abdigali.

In: Journal of Sulfur Chemistry, 01.01.2019.

Research output: Contribution to journal › Article

Boudebouz, I, Arrous, S, Plotnikov, E, Voronova, O & Bakibaev, A 2019, 'Synthesis and antioxidant activity of some new thioglycoluril derivatives', Journal of Sulfur Chemistry. https://doi.org/10.1080/17415993.2019.1588897
Boudebouz I, Arrous S, Plotnikov E, Voronova O, Bakibaev A. Synthesis and antioxidant activity of some new thioglycoluril derivatives. Journal of Sulfur Chemistry. 2019 Jan 1. https://doi.org/10.1080/17415993.2019.1588897
Boudebouz, Imene ; Arrous, Salah ; Plotnikov, Evgenii ; Voronova, Olesya ; Bakibaev, Abdigali. / Synthesis and antioxidant activity of some new thioglycoluril derivatives. In: Journal of Sulfur Chemistry. 2019.
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