A series of acetylene derivatives of thiazole using Sonogashira cross-coupling method was synthesized and evaluated in vivo for their anti-inflammatory activity. Four compounds exhibited a good anti-inflammatory activity and two inhibited soybean lipoxygenase.
|Number of pages||6|
|Journal||Khimiya Geterotsiklicheskikh Soedinenii|
|Publication status||Published - 11 Jul 2006|
- Ethynyl thiazoles
- Lipoxygenase (LOX)
ASJC Scopus subject areas
- Organic Chemistry