Abstract
A series of acetylene derivatives of thiazole using Sonogashira cross-coupling method was synthesized and evaluated in vivo for their anti-inflammatory activity. Four compounds exhibited a good anti-inflammatory activity and two inhibited soybean lipoxygenase.
| Original language | English |
|---|---|
| Pages (from-to) | 769-774 |
| Number of pages | 6 |
| Journal | Khimiya Geterotsiklicheskikh Soedinenii |
| Issue number | 5 |
| Publication status | Published - 11 Jul 2006 |
| Externally published | Yes |
Keywords
- Anti-inflammatory
- Ethynyl thiazoles
- Lipoxygenase (LOX)
ASJC Scopus subject areas
- Organic Chemistry
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Geronikaki, A., Vasilevsky, S., Hadjipavlou-Litina, D., Lagunin, A., & Poroikov, B. V. (2006). Synthesis and anti-inflammatory activity of ethynylthiazoles. Khimiya Geterotsiklicheskikh Soedinenii, (5), 769-774.