Abstract
A series of acetylene derivatives of thiazole using Sonogashira cross-coupling method was synthesized and evaluated in vivo for their anti-inflammatory activity. Four compounds exhibited a good anti-inflammatory activity and two inhibited soybean lipoxygenase.
Original language | English |
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Pages (from-to) | 769-774 |
Number of pages | 6 |
Journal | Khimiya Geterotsiklicheskikh Soedinenii |
Issue number | 5 |
Publication status | Published - 11 Jul 2006 |
Externally published | Yes |
Keywords
- Anti-inflammatory
- Ethynyl thiazoles
- Lipoxygenase (LOX)
ASJC Scopus subject areas
- Organic Chemistry