Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target

E. N. Bolbasov, M. Rybachuk, A. S. Golovkin, L. V. Antonova, E. V. Shesterikov, A. I. Malchikhina, V. A. Novikov, Y. G. Anissimov, S. I. Tverdokhlebov

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.

Original languageEnglish
Pages (from-to)281-284
Number of pages4
JournalMaterials Letters
Volume132
DOIs
Publication statusPublished - 1 Oct 2014

Fingerprint

Polycaprolactone
Sputter deposition
Durapatite
Hydroxyapatite
plasma jets
Surface treatment
Polymers
Plasmas
polymers
biocompatibility
Biocompatibility
Glow discharges
wettability
cultured cells
glow discharges
Free energy
attachment
Sputtering
Wetting
radio frequencies

Keywords

  • Biomaterials
  • Calcium-phosphate
  • Magnetron sputter deposition
  • Polymers

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering
  • Mechanics of Materials

Cite this

Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target. / Bolbasov, E. N.; Rybachuk, M.; Golovkin, A. S.; Antonova, L. V.; Shesterikov, E. V.; Malchikhina, A. I.; Novikov, V. A.; Anissimov, Y. G.; Tverdokhlebov, S. I.

In: Materials Letters, Vol. 132, 01.10.2014, p. 281-284.

Research output: Contribution to journalArticle

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AU - Bolbasov, E. N.

AU - Rybachuk, M.

AU - Golovkin, A. S.

AU - Antonova, L. V.

AU - Shesterikov, E. V.

AU - Malchikhina, A. I.

AU - Novikov, V. A.

AU - Anissimov, Y. G.

AU - Tverdokhlebov, S. I.

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AB - Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.

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