Abstract
Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.
| Original language | English |
|---|---|
| Pages (from-to) | 281-284 |
| Number of pages | 4 |
| Journal | Materials Letters |
| Volume | 132 |
| DOIs | |
| Publication status | Published - 1 Oct 2014 |
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Keywords
- Biomaterials
- Calcium-phosphate
- Magnetron sputter deposition
- Polymers
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Mechanical Engineering
- Mechanics of Materials
Cite this
Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target. / Bolbasov, E. N.; Rybachuk, M.; Golovkin, A. S.; Antonova, L. V.; Shesterikov, E. V.; Malchikhina, A. I.; Novikov, V. A.; Anissimov, Y. G.; Tverdokhlebov, S. I.
In: Materials Letters, Vol. 132, 01.10.2014, p. 281-284.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target
AU - Bolbasov, E. N.
AU - Rybachuk, M.
AU - Golovkin, A. S.
AU - Antonova, L. V.
AU - Shesterikov, E. V.
AU - Malchikhina, A. I.
AU - Novikov, V. A.
AU - Anissimov, Y. G.
AU - Tverdokhlebov, S. I.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.
AB - Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.
KW - Biomaterials
KW - Calcium-phosphate
KW - Magnetron sputter deposition
KW - Polymers
UR - http://www.scopus.com/inward/record.url?scp=84903991483&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903991483&partnerID=8YFLogxK
U2 - 10.1016/j.matlet.2014.06.115
DO - 10.1016/j.matlet.2014.06.115
M3 - Article
AN - SCOPUS:84903991483
VL - 132
SP - 281
EP - 284
JO - Materials Letters
JF - Materials Letters
SN - 0167-577X
ER -