Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target

E. N. Bolbasov, M. Rybachuk, A. S. Golovkin, L. V. Antonova, E. V. Shesterikov, A. I. Malchikhina, V. A. Novikov, Y. G. Anissimov, S. I. Tverdokhlebov

The Weinberg Research Center

Research output: Contribution to journal › Article

21 Citations (Scopus)

Abstract

Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar⁺ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.

Original language	English
Pages (from-to)	281-284
Number of pages	4
Journal	Materials Letters
Volume	132
DOIs	https://doi.org/10.1016/j.matlet.2014.06.115
Publication status	Published - 1 Oct 2014

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Keywords

Biomaterials
Calcium-phosphate
Magnetron sputter deposition
Polymers

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Mechanical Engineering
Mechanics of Materials

Cite this

Bolbasov, E. N., Rybachuk, M., Golovkin, A. S., Antonova, L. V., Shesterikov, E. V., Malchikhina, A. I., Novikov, V. A., Anissimov, Y. G., & Tverdokhlebov, S. I. (2014). Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target. Materials Letters, 132, 281-284. https://doi.org/10.1016/j.matlet.2014.06.115

Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target. / Bolbasov, E. N.; Rybachuk, M.; Golovkin, A. S.; Antonova, L. V.; Shesterikov, E. V.; Malchikhina, A. I.; Novikov, V. A.; Anissimov, Y. G.; Tverdokhlebov, S. I.

In: Materials Letters, Vol. 132, 01.10.2014, p. 281-284.

Research output: Contribution to journal › Article

Bolbasov, EN, Rybachuk, M, Golovkin, AS, Antonova, LV, Shesterikov, EV, Malchikhina, AI, Novikov, VA, Anissimov, YG & Tverdokhlebov, SI 2014, 'Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target', Materials Letters, vol. 132, pp. 281-284. https://doi.org/10.1016/j.matlet.2014.06.115

Bolbasov, E. N. ; Rybachuk, M. ; Golovkin, A. S. ; Antonova, L. V. ; Shesterikov, E. V. ; Malchikhina, A. I. ; Novikov, V. A. ; Anissimov, Y. G. ; Tverdokhlebov, S. I. / Surface modification of poly(l-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target. In: Materials Letters. 2014 ; Vol. 132. pp. 281-284.

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abstract = "Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.",

keywords = "Biomaterials, Calcium-phosphate, Magnetron sputter deposition, Polymers",

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AU - Golovkin, A. S.

AU - Antonova, L. V.

AU - Shesterikov, E. V.

AU - Malchikhina, A. I.

AU - Novikov, V. A.

AU - Anissimov, Y. G.

AU - Tverdokhlebov, S. I.

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AB - Surface modification of poly(l lactide) (l-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of l-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of l-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to l-PLA.

KW - Biomaterials

KW - Calcium-phosphate

KW - Magnetron sputter deposition

KW - Polymers

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Access to Document

10.1016/j.matlet.2014.06.115