99mTc-HMPAO-labeled autologous leukocyte SPECT/CT for diagnosis of bacterial endocarditis of the prosthetic pulmonary conduit

A clinical case

Svetlana Ivanovna Sazonova, Julia Nikolaevna Ilyushenkova, Konstantin Valer’Evich Zavadovsky, Yuri Borisovich Lishmanov

Research output: Contribution to journalArticle

Abstract

In this paper, wepresent a case of bacterial endocarditis of the prostheticpulmonary conduitfoundin a 26-year-oldman. Anechocardiography study around the pulmonary valve showed the presence of a floating mass attached to the wall of the conduit. This formation was thought to be a floating calcific leaflet of the conduit or a developed vegetation of the conduit. Due to the uncertainty of the results, pulmonary multidetector row computed tomography (MDCT) angiography was performed. TheMDCTexamination showed the presence of a floating 4 × 8-mm sized mass in the pulmonary conduit. Taking into account the patient’s complaints, medical history data, and clinical-instrumental examination, myocardial scintigraphy with 99mTc-HMPAO-labelled autologous leukocytes combined with CT (99mTc-HMPAO-SPECT/CT) was performed. Based on overlaying of the scintigraphic images and the MDCT aortography scans, anatomic localization of the pathologic accumulation was found in a projection of the pulmonary valve prosthesis. Surgical intervention, with cardiopulmonary bypass, was performed for replacement of the valve-containing conduit. Pathomorphologic study of the surgical material confirmed the hypothesis of bacterial endocarditis. Therefore, hybrid technologies such as99mTc-HMPAO-SPECT/CT contribute to the earlier and more precise diagnosis of infectious endocarditis, avoiding many errors associated with patient treatment and the development of complications.

Original languageEnglish
Article numbere34073
JournalIranian Journal of Radiology
Volume14
Issue number1
DOIs
Publication statusPublished - 1 Jan 2017

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Technetium Tc 99m Exametazime
Bacterial Endocarditis
Pulmonary Valve
Multidetector Computed Tomography
Leukocytes
Aortography
Lung
Myocardial Perfusion Imaging
Endocarditis
Cardiopulmonary Bypass
Prostheses and Implants
Uncertainty
Technology
Single Photon Emission Computed Tomography Computed Tomography
Therapeutics
Computed Tomography Angiography

Keywords

  • Bacterial endocarditis
  • Inflammation
  • SPECT/CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

99mTc-HMPAO-labeled autologous leukocyte SPECT/CT for diagnosis of bacterial endocarditis of the prosthetic pulmonary conduit : A clinical case. / Sazonova, Svetlana Ivanovna; Ilyushenkova, Julia Nikolaevna; Zavadovsky, Konstantin Valer’Evich; Lishmanov, Yuri Borisovich.

In: Iranian Journal of Radiology, Vol. 14, No. 1, e34073, 01.01.2017.

Research output: Contribution to journalArticle

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