TY - JOUR
T1 - Structure and properties of biodegradable PLLA/ZnO composite membrane produced via electrospinning
AU - Goncharova, Daria A.
AU - Bolbasov, Evgeny N.
AU - Nemoykina, Anna L.
AU - Aljulaih, Ali A.
AU - Tverdokhlebova, Tamara S.
AU - Kulinich, Sergei A.
AU - Svetlichnyi, Valery A.
N1 - Funding Information:
dressings with prolonged action for treatment of purulent-inflammatory diseases of the skin and other soft tissues. Supplementary Materials: The following are available online at www.mdpi.com/xxx/s1, Figure S1: SEM images and corresponding EDX maps of carbon (C Kα1), zinc (Zn Kα1), and oxygen (O Kα1) Supplementary Materials: The following are available online at https://www.mdpi.com/1996-194 4/14/1/2/s1, Figure S1: SEM images and corresponding EDX maps of carbon (C Kα1), zinc (Zn Author Contributions: E.N.B. and V.A.S.: conceptualization; methodology. T.S.T. and D.A.G.: Kα1), and oxygenvalidat(O Kion;α1)forobtainedmal analyforsis. theA.A.samples.A.: investigation; formal analysis. D.A.G. and A.L.N.: writing— draft. D.A.G., E.N.B. and S.A.K.: writing—review and editing; visualization. All authors have read and agreed to the publishedversion of the manuscript. validation; formal analysis. A.A.A.: investigation; formal analysis. D.A.G. and A.L.N.: writing— draft. D.A.G., EF.Nu.nBd.ianngd:TSh.iAsr.Kes.:eawrcrihti wnga—sfurnedveiedw byatnhde eTodmitsinkgS;tavties uUanlivizeartsioitny.C Aomll apueittthivoresnhesas vIme rperaodvement andagreedtotheProgpublishedram. D.A.versionG was suofpported bythe manuscript.a scholarship program of the President of the Russian Federa-tion for young scientists and post-graduate students (SP-2018 Competition). Funding: This research was funded by the Tomsk State University Competitiveness Improvement Program. D.A.G was supported by a scholarship program of the President of the Russian Federation for young scientists and post-graduate students (SP-2018 Competition).
Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021/1/1
Y1 - 2021/1/1
N2 - These days, composite materials based on polymers and inorganic nanoparticles (NPs) are widely used in optoelectronics and biomedicine. In this work, composite membranes of polylactic acid and ZnO NPs containing 5–40 wt.% of the latter NPs were produced by means of electrospinning. For the first time, polymer material loaded with up to 40 wt.% of ZnO NPs (produced via laser ablation in air and having non-modified surface) was used to prepare fiber-based composite membranes. The morphology, phase composition, mechanical, spectral and antibacterial properties of the membranes were tested by a set of analytical techniques including SEM, XRD, FTIR, UV-vis, and photoluminescence spectroscopy. Antibacterial activity of the materials was evaluated following standard procedures (ISO 20743:2013) and using S. aureus and E. coli bacteria. It is shown that incorporation of 5–10 wt.% of NPs led to improved mechanical properties of the composite membranes, while further increase of ZnO content up to 20 wt.% and above resulted in their noticeable deterioration. At the same time, the antibacterial properties of ZnO-rich membranes were more pronounced, which is explained by a larger number of surface-exposed ZnO NPs, in addition to those embedded into the bulk of fiber material.
AB - These days, composite materials based on polymers and inorganic nanoparticles (NPs) are widely used in optoelectronics and biomedicine. In this work, composite membranes of polylactic acid and ZnO NPs containing 5–40 wt.% of the latter NPs were produced by means of electrospinning. For the first time, polymer material loaded with up to 40 wt.% of ZnO NPs (produced via laser ablation in air and having non-modified surface) was used to prepare fiber-based composite membranes. The morphology, phase composition, mechanical, spectral and antibacterial properties of the membranes were tested by a set of analytical techniques including SEM, XRD, FTIR, UV-vis, and photoluminescence spectroscopy. Antibacterial activity of the materials was evaluated following standard procedures (ISO 20743:2013) and using S. aureus and E. coli bacteria. It is shown that incorporation of 5–10 wt.% of NPs led to improved mechanical properties of the composite membranes, while further increase of ZnO content up to 20 wt.% and above resulted in their noticeable deterioration. At the same time, the antibacterial properties of ZnO-rich membranes were more pronounced, which is explained by a larger number of surface-exposed ZnO NPs, in addition to those embedded into the bulk of fiber material.
KW - Antibacterial properties
KW - PLLA/ZnO composite membranes
KW - Pulsed laser ablation
KW - ZnO nanoparticles
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U2 - 10.3390/ma14010002
DO - 10.3390/ma14010002
M3 - Article
AN - SCOPUS:85098773151
VL - 14
SP - 1
EP - 13
JO - Materials
JF - Materials
SN - 1996-1944
IS - 1
M1 - 2
ER -