Abstract
A range of novel γ- and δ-sultams was prepared by intramolecular [4+2] cycloaddition of vinylsulfonamides with purely thermal activation and under high pressure. Using N-1-phenylethyl substituted vinylsulfonamides, enantiopure sultams were readily obtained, debenzylation of which provided the corresponding NH sultams in high yields in the case of δ-sultams.
Original language | English |
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Pages (from-to) | 167-190 |
Number of pages | 24 |
Journal | Arkivoc |
Volume | 2007 |
Issue number | 5 |
Publication status | Published - 2007 |
Externally published | Yes |
Keywords
- Asymmetric synthesis
- Cycloadditions
- Debenzylation
- High pressure
- Sulfur heterocycles
ASJC Scopus subject areas
- Organic Chemistry