Stably Fluorescent Cell Line of Human Ovarian Epithelial Cancer Cells SK-OV-3ip-red

E. V. Konovalova, A. A. Shulga, S. P. Chumakov, Yu M. Khodarovich, Eui Jeon Woo, S. M. Deev

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Stable red fluorescing line of human ovarian epithelial cancer cells SK-OV-3ip-red was generated expressing gene coding for protein TurboFP635 (Katushka) fluorescing in the far-red spectrum region with excitation and emission peaks at 588 and 635 nm, respectively. Fluorescence of SK-OV-3ip-red line remained high during long-term cell culturing and after cryogenic freezing. The obtained cell line SK-OV-3ip-red can serve a basis for a model of a scattered tumor with numerous/extended metastases and used both for testing anticancer drugs inhibiting metastasis growth and for non-invasive monitoring of the growth dynamics with high precision.

Original languageEnglish
Pages (from-to)99-101
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume164
Issue number1
DOIs
Publication statusPublished - 1 Nov 2017
Externally publishedYes

Keywords

  • SK-OV-3ip
  • stable fluorescent cell line
  • TurboFP635 (Katushka)

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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