Abstract
For several years the treatment of metals like cp titanium and 316L stainless steel with concentrated chromosulfuric acid at high temperatures (230-240 °C) has formed the basis for preparing ultra-hydrophilic priming coats on these metals (Jennissen et al. Materialwiss. Werkstofftech. 30, 838-845, 1999). Metals treated in this way have been called surface-enhanced, displaying a characteristic ultrastructure, and can be easily modified to carry a biocoat of recombinant human bone morphogenetic protein 2 (rhBMP2). The major oxide on surface enhanced titanium is TiO 2. Thus this TiO 2-layer could be responsible for the ultra-hydrophilic properties of the priming coat. Irradiation of TiO 2 layers by ultraviolet light (Wang et al., Nature 388, 431-432, 1997) has been shown to endow these layers with ultra-hydrophilic properties (i.e. contact angles of ∼ 0°). However the ultra-hydrophilic TiO 2-layers produced by irradiation are unstable and revert to the original high contact angles of ∼ 70° within several days. The question of whether the ultra-hydrophilic surfaces prepared by the chromosulfuric acid method show long-term stability was therefore important to answer. In addition the question if rhBMP-2 immobilized on such a surface will retain its biological activity was of great interest. In this paper it will be shown that ultrahydrophilic titanium mini-plates retain their ultra-hydrophilicity with contact angles of 0-8° unchanged for at least 50 days and support the immobilization of rhBMP-2 in a biologically active form.
Original language | English |
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Pages (from-to) | 1106-1112 |
Number of pages | 7 |
Journal | Materialwissenschaft und Werkstofftechnik |
Volume | 34 |
Issue number | 12 |
DOIs | |
Publication status | Published - Dec 2003 |
Externally published | Yes |
Keywords
- 316L steel
- Chromosulfuric acid
- Cobalt chromium alloy
- Contact angle hysteresis
- Inverse Lotus Effect
- Rockwell adhesion test
- TiO
- Titanium
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering