Stability of gold nanoparticles functionalized with aminoacids

M. C. Ramirez-Camacho, I. Tusovskaya, A. Susarrey-Arce, A. N. Pestryakov, N. Bogdanchikova

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

While bio(organic-inorganic) compatibility and absence of cytotoxicity are crucial to create a successful nanocarrier for applications in biosensing and drug delivery [1], the study of its stability before commercialization is quite important. In the present work, the stability of gold nanoparticles (AuNPs) functionalized with L-Cysteine (Cys) and Cysteine-Glycine (Cys-Gly) was studied. The AuNPs surface modification with Cys and CysGly was performed to improve their biocompatibility [2] and, after that, the stability of capped AuNPs was investigated. The synthetized AuNPs using 10 μM of cysteine and 20 μM of Cys demonstrated stability after 1 month of storage, while all other concentration ratios resulted in the formation of chain-like conglomerates. For AuNP capped with CysGly all modifier concentrations led to stable samples within 1 month of storage.

Original languageEnglish
Title of host publicationAdvanced Materials Research
Pages253-258
Number of pages6
Volume880
DOIs
Publication statusPublished - 2014
Event10th International Conference on Prospects of Fundamental Sciences Development, PFSD-2013 - Tomsk, Russian Federation
Duration: 23 Apr 201326 Apr 2013

Publication series

NameAdvanced Materials Research
Volume880
ISSN (Print)10226680

Other

Other10th International Conference on Prospects of Fundamental Sciences Development, PFSD-2013
CountryRussian Federation
CityTomsk
Period23.4.1326.4.13

Keywords

  • Cysteine
  • Functionalization
  • Glycine
  • Gold
  • Gold nanoparticles stabilization
  • Nanoparticles
  • Sodium citrate

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Ramirez-Camacho, M. C., Tusovskaya, I., Susarrey-Arce, A., Pestryakov, A. N., & Bogdanchikova, N. (2014). Stability of gold nanoparticles functionalized with aminoacids. In Advanced Materials Research (Vol. 880, pp. 253-258). (Advanced Materials Research; Vol. 880). https://doi.org/10.4028/www.scientific.net/AMR.880.253