Sputtered Si and Mg doped hydroxyapatite for biomedical applications

Alina Vladescu, Cosmin Mihai Cotrut, Funda Ak Azem, Mirosław Bramowicz, Iulian Pana, Viorel Braic, Isil Birlik, Adrian Kiss, Mariana Braic, Radwan Abdulgader, Robin Booysen, Sławomir Kulesza, Thomas K. Monsees

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Hydroxyapatite (HAP) coatings are applied on metallic implant materials to combine mechanical properties of metallic material with bioactivity abilities of HAP ceramic. In this study, HAP coatings with additions of Si and Mg are proposed to be deposited on Ti6Al4V substrates by RF magnetron sputtering. Chemical bonding, morphology, topography and corrosion resistance in simulated body fluids (SBF) of the coatings were investigated. Additionally, mechanical and biological properties of the coatings were evaluated. It was found that the addition of Si and Mg does not influence the formation of a HAP phase. All the coatings exhibited smooth surface and uniform growth, without defects or cracks. Both hardness and elastic modulus of the coated samples decrease with Mg addition in the HAP-Si structure. Both Mg and Si addition into HAP coatings were found to enhance the corrosion resistance of the Ti6Al4V alloy in the SBF solution. Coatings with low Mg content exhibited better corrosion performance. All the coatings investigated were biocompatible, as demonstrated by SaOS-2 bone cell attachment and growth. However, cell proliferation and morphology were inferior on samples with the highest Mg content.

Original languageEnglish
Article number025011
JournalBiomedical Materials (Bristol)
Volume13
Issue number2
DOIs
Publication statusPublished - 30 Jan 2018

Keywords

  • bioactive coatings
  • cell viability
  • corrosion resistance
  • elastic modulus
  • hardness
  • magnetron sputtering
  • sarcoma cells

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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  • Cite this

    Vladescu, A., Mihai Cotrut, C., Ak Azem, F., Bramowicz, M., Pana, I., Braic, V., Birlik, I., Kiss, A., Braic, M., Abdulgader, R., Booysen, R., Kulesza, S., & Monsees, T. K. (2018). Sputtered Si and Mg doped hydroxyapatite for biomedical applications. Biomedical Materials (Bristol), 13(2), [025011]. https://doi.org/10.1088/1748-605X/aa9718