Spectral characteristics and antioxidant properties of tannic acid immobilized on collagen drug-delivery systems

Madalina Georgiana Albu, Mihaela Violeta Ghica, Maria Giurginca, Viorica Trandafir, Lacramioara Popa, Cosmin Cotrut

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Tannic acid, a biologic active polyphenol, performs antiviral, antibacterial and antioxidant activity. At the same time, collagen as a natural polymer is widely used in medicine as biomaterial scaffold for tissue regeneration of different types of connective tissue. The aim of this study is to obtain some composite biomaterials with antioxidant activity based on collagen-tannic acid which can be used both as topical formulations and as bioactive dressing for skin wounds. Biomaterials like hydrogels and matrices from collagen gels and tannic acid are obtained by different techniques of conditioning or drying. The antioxidant activity of collagen-tannic acid hydrogels is investigated by chemiluminescence technique (CL) and fluorescence spectroscopy (SF). The chemical-structural characterization of collagen-tannic acid matrices is investigated by UV-VIS-NIR and FT-IR-ATR spectroscopy. The in vitro kinetic release both for collagen hydrogels and matrices proves that these biomaterials can act as bioactive systems for controlled release of tannic acid.

Original languageEnglish
Pages (from-to)666-672
Number of pages7
JournalRevista de Chimie
Volume60
Issue number7
Publication statusPublished - 1 Jan 2009
Externally publishedYes

Fingerprint

Tannins
Antioxidants
Collagen
Biocompatible Materials
Biomaterials
Hydrogels
Acids
Natural polymers
Tissue regeneration
Chemiluminescence
Fluorescence spectroscopy
Polyphenols
Scaffolds (biology)
Medicine
Antiviral Agents
Drug Delivery Systems
Infrared spectroscopy
Skin
Drying
Gels

Keywords

  • Antioxidant activity
  • Biomaterials
  • Collagen
  • Kinetic release
  • Tannic acid

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Spectral characteristics and antioxidant properties of tannic acid immobilized on collagen drug-delivery systems. / Albu, Madalina Georgiana; Ghica, Mihaela Violeta; Giurginca, Maria; Trandafir, Viorica; Popa, Lacramioara; Cotrut, Cosmin.

In: Revista de Chimie, Vol. 60, No. 7, 01.01.2009, p. 666-672.

Research output: Contribution to journalArticle

Albu, MG, Ghica, MV, Giurginca, M, Trandafir, V, Popa, L & Cotrut, C 2009, 'Spectral characteristics and antioxidant properties of tannic acid immobilized on collagen drug-delivery systems', Revista de Chimie, vol. 60, no. 7, pp. 666-672.
Albu, Madalina Georgiana ; Ghica, Mihaela Violeta ; Giurginca, Maria ; Trandafir, Viorica ; Popa, Lacramioara ; Cotrut, Cosmin. / Spectral characteristics and antioxidant properties of tannic acid immobilized on collagen drug-delivery systems. In: Revista de Chimie. 2009 ; Vol. 60, No. 7. pp. 666-672.
@article{33e1a2d071d9448ba2e6107ca0a70145,
title = "Spectral characteristics and antioxidant properties of tannic acid immobilized on collagen drug-delivery systems",
abstract = "Tannic acid, a biologic active polyphenol, performs antiviral, antibacterial and antioxidant activity. At the same time, collagen as a natural polymer is widely used in medicine as biomaterial scaffold for tissue regeneration of different types of connective tissue. The aim of this study is to obtain some composite biomaterials with antioxidant activity based on collagen-tannic acid which can be used both as topical formulations and as bioactive dressing for skin wounds. Biomaterials like hydrogels and matrices from collagen gels and tannic acid are obtained by different techniques of conditioning or drying. The antioxidant activity of collagen-tannic acid hydrogels is investigated by chemiluminescence technique (CL) and fluorescence spectroscopy (SF). The chemical-structural characterization of collagen-tannic acid matrices is investigated by UV-VIS-NIR and FT-IR-ATR spectroscopy. The in vitro kinetic release both for collagen hydrogels and matrices proves that these biomaterials can act as bioactive systems for controlled release of tannic acid.",
keywords = "Antioxidant activity, Biomaterials, Collagen, Kinetic release, Tannic acid",
author = "Albu, {Madalina Georgiana} and Ghica, {Mihaela Violeta} and Maria Giurginca and Viorica Trandafir and Lacramioara Popa and Cosmin Cotrut",
year = "2009",
month = "1",
day = "1",
language = "English",
volume = "60",
pages = "666--672",
journal = "Revista de Chimie",
issn = "0034-7752",
publisher = "Syscom 18 SRL",
number = "7",

}

TY - JOUR

T1 - Spectral characteristics and antioxidant properties of tannic acid immobilized on collagen drug-delivery systems

AU - Albu, Madalina Georgiana

AU - Ghica, Mihaela Violeta

AU - Giurginca, Maria

AU - Trandafir, Viorica

AU - Popa, Lacramioara

AU - Cotrut, Cosmin

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Tannic acid, a biologic active polyphenol, performs antiviral, antibacterial and antioxidant activity. At the same time, collagen as a natural polymer is widely used in medicine as biomaterial scaffold for tissue regeneration of different types of connective tissue. The aim of this study is to obtain some composite biomaterials with antioxidant activity based on collagen-tannic acid which can be used both as topical formulations and as bioactive dressing for skin wounds. Biomaterials like hydrogels and matrices from collagen gels and tannic acid are obtained by different techniques of conditioning or drying. The antioxidant activity of collagen-tannic acid hydrogels is investigated by chemiluminescence technique (CL) and fluorescence spectroscopy (SF). The chemical-structural characterization of collagen-tannic acid matrices is investigated by UV-VIS-NIR and FT-IR-ATR spectroscopy. The in vitro kinetic release both for collagen hydrogels and matrices proves that these biomaterials can act as bioactive systems for controlled release of tannic acid.

AB - Tannic acid, a biologic active polyphenol, performs antiviral, antibacterial and antioxidant activity. At the same time, collagen as a natural polymer is widely used in medicine as biomaterial scaffold for tissue regeneration of different types of connective tissue. The aim of this study is to obtain some composite biomaterials with antioxidant activity based on collagen-tannic acid which can be used both as topical formulations and as bioactive dressing for skin wounds. Biomaterials like hydrogels and matrices from collagen gels and tannic acid are obtained by different techniques of conditioning or drying. The antioxidant activity of collagen-tannic acid hydrogels is investigated by chemiluminescence technique (CL) and fluorescence spectroscopy (SF). The chemical-structural characterization of collagen-tannic acid matrices is investigated by UV-VIS-NIR and FT-IR-ATR spectroscopy. The in vitro kinetic release both for collagen hydrogels and matrices proves that these biomaterials can act as bioactive systems for controlled release of tannic acid.

KW - Antioxidant activity

KW - Biomaterials

KW - Collagen

KW - Kinetic release

KW - Tannic acid

UR - http://www.scopus.com/inward/record.url?scp=70249138758&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70249138758&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:70249138758

VL - 60

SP - 666

EP - 672

JO - Revista de Chimie

JF - Revista de Chimie

SN - 0034-7752

IS - 7

ER -