Spatially selective modification of PLLA surface: From hydrophobic to hydrophilic or to repellent

Kristina Bastekova, Olga Guselnikova, Pavel Postnikov, Roman Elashnikov, Martin Kunes, Zdenka Kolska, Vaclav Švorčík, Oleksiy Lyutakov

    Research output: Contribution to journalArticlepeer-review

    14 Citations (Scopus)


    A universal approach to controlled surface modification of polylactic acid (PLLA) films using diazonium chemistry was proposed. The multistep procedure includes surface activation of PLLA by argon plasma treatment and chemical activation of arenediazonium tosylates by NaBH 4 . The surface of PLLA film was grafted with different functional organic groups (OFGs), changing the PLLA surface properties (wettability, morphology, zeta potential, chemical composition, and mechanical response). Three approaches of OFG grafting were examined: (i) plasma treatment following by PLLA immersion into diazonium salt aqueous solution; (ii) grafting of PLLA surface through the reaction with chemically created aryl radicals; (iii) mutual combination of both methods The best results were achieved in the last case, where the previous plasma treatment was combined with further reaction of PLLA surface with generated aryl radicals. Using this method PLLA surface was successfully grafted with amino, carboxyl, aliphatic and fluorinated OFGs. Further investigation of surface properties from potential biological and medical points of view was performed using zeta potential, biodegradation and biofouling tests. It was shown that proposed technique allows preparation of biorepellent or bioabsorptive surfaces, tuning of PLLA biodegradation rate and nanomechanical properties, as well as the introduction of inverse properties (such as hydrophilic and hydrophobic) on both sides of PLLA films.

    Original languageEnglish
    Pages (from-to)226-234
    Number of pages9
    JournalApplied Surface Science
    Publication statusPublished - 1 Mar 2017


    • Diazonium salt
    • Plasma
    • PLLA
    • Surface modification
    • Surface properties

    ASJC Scopus subject areas

    • Surfaces, Coatings and Films

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