Size controlled hydroxyapatite and calcium carbonate particles: Synthesis and their application as templates for SERS platform

B. V. Parakhonskiy, Yu I. Svenskaya, A. M. Yashchenok, H. A. Fattah, O. A. Inozemtseva, F. Tessarolo, R. Antolini, D. A. Gorin

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

An elegant route for hydroxyapatite (HA) particle synthesis via ionic exchange reaction is reported. Calcium carbonate particles (CaCO3) were recrystallized into HA beads in water solution with phosphate ions. The size of initial CaCO3 particles was controlled upon the synthesis by varying the amount of ethylene glycol (EG) in aqueous solution. The average size of HA beads ranged from 0.6±0.1 to 4.3±1.1μm. Silver nanoparticles were deposited on the surface of HA and CaCO3 particles via silver mirror reaction. Surface enhanced Raman scattering of silver functionalized beads was demonstrated by detecting Rhodamine B. CaCO3 and HA particles have a great potential for design of carrier which can provide diagnostic and therapeutic functions.

Original languageEnglish
Pages (from-to)243-248
Number of pages6
JournalColloids and Surfaces B: Biointerfaces
Volume118
DOIs
Publication statusPublished - 1 Jun 2014
Externally publishedYes

Keywords

  • Calcium carbonate
  • Hydroxyapatite
  • Particles
  • SERS
  • Silver nanoparticles
  • Vaterite

ASJC Scopus subject areas

  • Biotechnology
  • Colloid and Surface Chemistry
  • Physical and Theoretical Chemistry
  • Surfaces and Interfaces
  • Medicine(all)

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    Parakhonskiy, B. V., Svenskaya, Y. I., Yashchenok, A. M., Fattah, H. A., Inozemtseva, O. A., Tessarolo, F., Antolini, R., & Gorin, D. A. (2014). Size controlled hydroxyapatite and calcium carbonate particles: Synthesis and their application as templates for SERS platform. Colloids and Surfaces B: Biointerfaces, 118, 243-248. https://doi.org/10.1016/j.colsurfb.2014.03.053