Simple synthesis of 3-acyl-5-alkyl(aryl)isoxazoles from terminal alkynes and nitrates of alkaline metals or ammonium

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A simple and general synthesis of 3-acyl-5-alkyl(axyl)isoxazoles by reaction of terminal alkynes with nitrates in acetic acid in the presence of SO3 or alkaline salts is described.

Original languageEnglish
Pages (from-to)370-376
Number of pages7
JournalCentral European Journal of Chemistry
Issue number3
Publication statusPublished - 1 Jul 2005



  • Alkynes
  • Isoxazoles
  • Nitrates
  • Sulfur trioxide

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

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