Silver release and antimicrobial properties of PMMA films doped with silver ions, nano-particles and complexes

O. Lyutakov, I. Goncharova, S. Rimpelova, K. Kolarova, J. Svanda, V. Svorcik

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Materials prepared on the base of bioactive silver compounds have become more and more popular due to low microbial resistance to silver. In the present work, the efficiency of polymethylmethacrylate (PMMA) thin films doped with silver ions, nanoparticles and silver-imidazole polymer complex was studied by a combination of AAS, XPS and AFM techniques. The biological activities of the proposed materials were discussed in view of the rate of silver releasing from the polymer matrix. Concentrations of Ag active form were estimated by its ability to interact with l-cysteine using electronic circular dichroism spectroscopy. Rates of the released silver were compared with the biological activity in dependence on the form of embedded silver. Antimicrobial properties of doped polymer films were studied using two bacterial strains: Staphylococcus epidermidis and Escherichia coli. It was found that PMMA films doped with Ag+ had greater activity than those doped with nanoparticles and silver-imidazole polymeric complexes. However, the antimicrobial efficiency of Ag+ doped films was only short-term. Contrary, the antimicrobial activity of silver-imidazole/PMMA films increased in time of sample soaking.

Original languageEnglish
Pages (from-to)534-540
Number of pages7
JournalMaterials Science and Engineering C
Volume49
DOIs
Publication statusPublished - 1 Apr 2015
Externally publishedYes

Fingerprint

Polymethyl Methacrylate
Silver
silver
Ions
ions
activity (biology)
imidazoles
Bioactivity
Silver Compounds
Silver compounds
polymers
silver compounds
Circular dichroism spectroscopy
Nanoparticles
nanoparticles
staphylococcus
soaking
cysteine
low resistance
releasing

Keywords

  • Antimicrobial properties
  • Doped polymer
  • Silver helical complex
  • Silver nanoparticles

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Silver release and antimicrobial properties of PMMA films doped with silver ions, nano-particles and complexes. / Lyutakov, O.; Goncharova, I.; Rimpelova, S.; Kolarova, K.; Svanda, J.; Svorcik, V.

In: Materials Science and Engineering C, Vol. 49, 01.04.2015, p. 534-540.

Research output: Contribution to journalArticle

Lyutakov, O. ; Goncharova, I. ; Rimpelova, S. ; Kolarova, K. ; Svanda, J. ; Svorcik, V. / Silver release and antimicrobial properties of PMMA films doped with silver ions, nano-particles and complexes. In: Materials Science and Engineering C. 2015 ; Vol. 49. pp. 534-540.
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